Tag: Clinical-Nursing

  • NURS 6521: ADVANCED PHARMACOLOGY – Week 8: Infections

    NURS 6521: ADVANCED PHARMACOLOGY – Week 8: Infections

    Week 8: Infections

    Prior to the H1N1 influenza pandemic in 2009, it had been more than 40 years since an infectious virus had resulted in such substantial illness, hospitalizations, and deaths on a global scale (CDC, 2010). This can be attributed to improved prevention such as proper hygiene, as well as vaccinations and other drug therapies. However, as the H1N1 pandemic illustrates, infections are sometimes unavoidable even when appropriate prevention methods are implemented. In clinical settings, patients present with various infections including common disorders such as flus and colds, as well as disorders that require more extensive treatment and care such as the human immunodeficiency virus (HIV) or tuberculosis (TB). As an advanced practice nurse, you must evaluate patients presenting with symptoms of infections and recommend appropriate drug treatments.

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    This week you begin to explore infections by considering issues surrounding the prevalence, management, and education about HIV/AIDS. You also examine viral and bacterial infections, as well as the appropriate use of antimicrobial agents.

    Learning Objectives

    By the end of this week, students will:

    · Analyze reasons for the prevalence of HIV/AIDS

    · Analyze ways health care professionals can change society’s perceptions of HIV/AIDS

    · Analyze strategies to educate HIV positive patients on treatment and management

    · Analyze categories of antimicrobial agents NURS 6521: ADVANCED PHARMACOLOGY – Week 8: Infections

    · Differentiate between viral and bacterial infections

    · Analyze the relationship between infections and antimicrobial agents

    · Understand and apply key terms, concepts, and principles related to prescribing drugs to treat infections and infestations

    Photo Credit: E.M. Pasieka/ Science Photo Library/Getty Images

    Learning Resources

    This page contains the Learning Resources for this week. Be sure to scroll down the page to see all of this week’s assigned Learning Resources. To access select media resources, please use the media player below.

    Required Readings

    Note:
     
     To access this week’s required library resources, please click on the link to the Course Readings List, found in the 
     
    Course Materials
     
     section of your Syllabus.

    Arcangelo, V. P., & Peterson, A. M. (Eds.). (2013). 
    Pharmacotherapeutics for advanced practice: A practical approach
     (3rd ed.). Ambler, PA: Lippincott Williams & Wilkins.

    · Chapter 8, “Principles of Antimicrobial Therapy” (pp. 96–117)  This chapter covers factors that impact the selection of an antimicrobial treatment regimen. It also examines the clinical uses, adverse events, and drug interactions of various antimicrobial agents such as penicillin. NURS 6521: ADVANCED PHARMACOLOGY – Week 8: Infections

     

    · Chapter 12, “Fungal Infections of the Skin” (pp. 141–149)  This chapter explores the pathophysiology of several fungal infections of the skin as well as related drug treatments and examines the importance of patient education when managing these infections.

     

    · Chapter 14, “Bacterial Infections of the Skin” (pp. 158–172)  This chapter begins by examining causes of bacterial infections. It then explores the importance of selecting an appropriate agent for treating bacterial infections.

     

    · Chapter 32, “Urinary Tract Infection” (pp. 474–480)  This chapter covers drugs used to treat urinary tract infections and identifies special considerations when treating geriatric patients, pediatric patients, and women.

     

    · Chapter 35, “Sexually Transmitted Infections” (pp. 512–535)  This chapter outlines the causes, pathophysiology, and drug treatment of six sexually transmitted infections, including gonorrhea, syphilis, and human papilloma virus infection (HPV). It also examines the importance of selecting the proper agent and monitoring patient response to treatment. NURS 6521: ADVANCED PHARMACOLOGY – Week 8: Infections.

     

    · Chapter 48, “Human Immunodeficiency Virus” (pp. 748–762)  This chapter presents the causes, pathophysiology, diagnostic criteria, and prevention methods for HIV. It also covers various methods of drug treatment and patient factors to consider when selecting, administering, and managing drug treatments.

    Krummenacher, I., Cavassini, M., Bugnon, O., & Schneider, M. (2011). An interdisciplinary HIV-adherence program combining motivational interviewing and electronic antiretroviral drug monitoring. 
    AIDS Care, 23
    (5), 550–561.

    Note:
     Retrieved from the Walden Library databases.

     

    This article analyzes medication adherence in HIV patients and examines factors that increase adherence as well as factors that contribute to termination or discontinuation of treatment.

    Drugs.com. (2012). Retrieved from http://www.drugs.com/

     

    This website presents a comprehensive review of prescription and over-the-counter drugs including information on common uses and potential side effects. It also provides updates relating to new drugs on the market, support from health professionals, and a drug-drug interactions checker. NURS 6521: ADVANCED PHARMACOLOGY – Week 8: Infections.

    Scourfield, A., Waters, L., & Nelson, M. (2011). Drug combinations for HIV: What’s new? 
    Expert Review of Anti-Infective Therapy, 9
    (11), 1001–1011.

    Note:
     Retrieved from the Walden Library databases.

     

    This article examines current therapies and strategies for treating HIV patients. It also examines factors that impact selection of therapy, including drug interactions, personalization of therapy, costs, management of comorbidities, and patient response.

    Required Media

    Laureate Education, Inc. (Executive Producer). (2012). 
    Antimicrobials
    . Baltimore, MD: Author.

     

    This media presentation outlines principles of antimicrobial therapy

     

    Note:
     The approximate length of this media piece is 7 minutes.

    Optional Resources

    Mayer, K. H., & Krakower, D. (2012). Antiretroviral medication and HIV prevention: New steps forward and New Questions. Annals of Internal Medicine, 156(4), 312–314.

    Note:
    Retrieved from the Walden Library databases. NURS 6521: ADVANCED PHARMACOLOGY – Week 8: Infections

  • NURS 6521 Syllabus

    NURS 6521 Syllabus

    Student Support and Calendar Information

    So you have all key information available to you off-line, it is highly recommended that you print the following items for your reference:

    Syllabus, including the Course Schedule, located below as a linked PDF

    Term Calendar

    Student Support

    Photo Credit: Steve Hix/Fuse/Corbis/Getty Images

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    Credit Hours

    5 quarter hours

    Walden University assigns credit hours based on the number and type of assignments that enable students to achieve the course learning objectives. In general, each semester credit equals about 42 hours of total student work and each quarter credit equals about 28 hours of total student work. This time requirement represents an approximate average for undergraduate work and the minimum expectations for graduate work. The number and kind of activities estimated to fulfill time requirements will vary by degree level and student learning style, and by student familiarity with the delivery method and course content. NURS 6521 Syllabus.

    Course Description

    A solid foundation in the concepts and principles of drug therapy across the lifespan is essential to the work of advanced practice nurses. This course applies the advanced principles of pharmacology, including pharmacogenomics, pharmacokinetics and pharmacodynamics, by analysis of common drug classes prescribed by advanced practice nurses across the life span. Factors influencing successful therapy such as effectiveness, safety, acceptability, cost, genetic/environmental influences, complementary regimens, and patient behaviors are considered NURS 6521 Syllabus. Through this course, students prepare to examine complex decisions in the management and treatment of selected acute and chronic diseases across the lifespan through pharmacologic and non-pharmacologic agents. Advanced practice nursing students will have a more in-depth understanding of drug legislation and regulation for prescribing drugs.

    Course Prerequisites

    There are no prerequisites for this course.

    Learning Objectives

    By the end of this course, students will:

    Evaluate the impact of patient factors on pharmacokinetic and pharmacodynamic processes

    Analyze treatments for body system disorders

    Analyze factors that impact patient drug therapy plans

    Evaluate the impact of drug therapy on patient health outcomes

    Analyze the appropriate use of drugs based on classifications, indications, and patient factors

    Evaluate ethical and legal implications of prescribing drugs

    Analyze current issues related to drug treatments NURS 6521 Syllabus

    Click on the following link to access the SON Alignment of Learner Outcomes:

    Document: NURS 6521 SON Alignment of Learner Outcomes (PDF)

     

    Course Materials

    Students will be provided the following course materials. For missing, incorrect, or damaged materials, please contact the Student Support Team. Contact information for the Student Support Team can be located in the
    Student Support
    area of the course navigation menu.

    Course Texts

    Arcangelo, V. P., & Peterson, A. M. (Eds.). (2013).
    Pharmacotherapeutics for advanced practice: A practical approach
    (3rd ed.). Ambler, PA: Lippincott Williams & Wilkins.

    Other readings (journal articles, websites, book excerpts, etc.) are assigned throughout the course and may be found within each week and within the Course Schedule.

    Course Readings List

    The Course Readings List contains all of the required Walden Library resources for this course. Please click on the following link to access the list: v.

    NURS 6521 Course Readings List

     

    Media

    Assigned course media elements are found within the weekly Learning Resources pages and are available via a streaming media player or a hyperlink to the individual item.

    Dedicated Support for Course Media

    You may use the following e-mail address and toll-free number for any questions or concerns you have about media in the course. NURS 6521 Syllabus

    Course Assignments

    Participation in weekly Discussions
    : The exchange of ideas among colleagues engaged in scholarly inquiry is a key aspect of learning and is a requisite activity in this course. You are expected to participate each week by posting a response to a prompt or question in the weekly Discussion area. Discussion topics/questions are provided in the Discussion area under each weekly button. In addition, you are expected to respond to your fellow students’ postings. To count as participation, responses need to be thoughtful; that is, they must refer to the week’s readings, relevant issues in the news, information obtained from other sources, and/or ideas expressed in the postings of other class members. NURS 6521 Syllabus. You may ask questions or offer further information or links about the subject. Please pay attention to grammar and spelling, as consistently poorly written posts will receive grade penalties. In grading the required Discussion postings, your Instructor will be using the “Formative Evaluation Criteria for Discussion Board Assignments” rubric, located in the
    Course Information
    area.

    Note:
    Unless otherwise noted, initial postings to Discussions are due on or before
    Day 3
    , and response postings are due on or before
    Day 6
    . You are required to participate in the Discussion on
    at least three different days
    . It is important to adhere to the weekly time frame to allow others ample time to respond to your posting. In addition, you are expected to respond to questions directed toward your own initial posting in a timely manner.

    Application Assignments
    : The Application Assignments provide you with the opportunity to apply the skills and knowledge gained through the Learning Resources. See the
    Assignment
    area of specific weeks for detailed descriptions of the assignments. In grading the required Application Assignments, your Instructor will be using the “Formative Evaluative Criteria for Applications and Formal Papers” rubric located in the
    Course Information
    area. NURS 6521 Syllabus.

    Quizzes
    : The course contains 11 graded, open-book quizzes that have been designed to assess your understanding of the course topics. The quizzes are due by
    Day 7
    each week.

    Grading Criteria and Total Components of a Grade

    Course grades will be based on participation (postings) and completion of assignments listed below.

    A = 90% or better

    B = 80%–89%

    C = 70%–79%

    F = 69% or below

    Please see below for the policy on Incomplete (I) grades.

    Important Note:
    This course contains weighted grading. Assignments are weighted
    differently
    depending on their type. The total points achieved for each assignment will be weighted based on the percentage values noted in the
    Weighted Total (%)
    column of the table that follows.

    Assignment

    Total Points

    Percentage

    Discussions

    Participation in Discussions*

    Weeks 1-11 (100 points each)

    Rubric:

    Discussion Rubric

    1,100

    30%

    Application Assignments

    (5 Assignments, each worth 100 points)

    Week 2 Application Paper

    Week 4 Application Paper

    Week 6 Application Paper

    Week 8 Application Paper NURS 6521 Syllabus

    Week 10 Application Paper

    Rubric
    :
    Application Assignment Rubric

    500

    45%

    Quizzes

    Completion of Weekly Quizzes

    Week 1, 10 and 11 (40 points)

    Week 2 and 3 (25 points)

    Week 4, 5, and 6 (30 points)

    Week 7, 8 and 9 (35 points)

    365

    25%

    *Note:
    Each Discussion requires that you make one initial posting and at least two response postings to colleagues. Refer to the “Formative Evaluation Criteria for Discussion Board Assignments” rubric for posting details.

    Incomplete Grade Policy

    Per University policy, Incomplete grades can be granted only to students who have already met the minimum criteria for active weekly participation in a course (including weekly postings in online courses) and have completed at least 80% of other coursework. Incompletes can be awarded when, because of extenuating circumstances, a student has not met additional course requirements, including but not limited to written assignments, group projects, and research papers, as applicable. All Incomplete grades are awarded at the discretion of the course faculty. (Reproduced from Student Catalog) NURS 6521 Syllabus.

    Students who are eligible for an Incomplete must contact the course faculty to request the grade as soon as possible. Students who do not meet the criteria listed above will not be allowed to earn an Incomplete. If the Incomplete is approved, the Faculty Member will work with the student to outline the due date(s) for remaining work. Under no circumstances will the new due dates extend beyond 50 days from the last day of the term. Faculty will then have 10 days to assess the work and post the permanent grade before the University-allotted Incomplete time limit of 60 days expires. All Incomplete grades not resolved within the time allotted will convert to permanent grades of F.

    Feedback Schedule

    The Instructor will log into the course at least 3–4 times during the week to monitor the weekly
    Discussion
    area. Feedback will be provided via the
    Discussion
    area and/or the
    Announcements
    page. Requests for more specific feedback may be made in the
    Discussion
    area or in the
    Contact the Instructor
    thread.

    The Instructor will respond to at least one main post each week but will usually not respond to all posts.

    Feedback on all assignments will be provided by
    Day 7
    of the week following the one in which the assignment was due. For example, if your assignment was due in
    Week 3
    , you would receive feedback on that assignment by
    Day 7
    of
    Week 4
    . NURS 6521 Syllabus.

    Each Instructor has a unique way of providing feedback. If you think that you are not getting enough feedback, you are strongly encouraged to contact your Instructor and ask for more. Contact information for your Instructor can be found under the
    Contact the Instructor
    area. For more information on Instructor feedback, go to the Faculty Accessibility section of Faculty and Student Guidelines for Online Courses, located in the
    Guidelines and Policies
    area.

    Course Procedures

    All class Discussions take place in the weekly
    Discussion
    areas.

    Questions related to course content must be posted in the
    Discussion
    area or in the
    Contact the Instructor
    or
    Class Café
    areas. Please do not e-mail course-related questions to the Instructor or fellow classmates, as your questions are probably of interest to others in the class. Also, expect that feedback on your work may be posted in the
    Discussion
    area for the benefit of the entire class. However, private e-mailing between student and Instructor may be used for personal, confidential situations. NURS 6521 Syllabus.

    Please feel free to use the
    Class Café
    to initiate and participate in conversations not directly related to the course. This is an excellent opportunity to get to know other students better. The Instructor will browse the Café occasionally but generally will not respond to conversations posted there unless students have specific questions for the Instructor.

    Check the e-mail account that you use for official Walden University business on a regular basis. The expectation is that you are checking this e-mail account daily during the week. If you experience difficulty sending or receiving Walden e-mail, please contact the Student Support Team right away. Contact information for the Student Support Team is located in the
    Student Support
    area.

    Review all materials in the Course Information area, as well as the materials contained under each of the weekly buttons.
    Please note
    : There may be Optional Readings located within the Learning Resources section of each week in the course. You are encouraged to explore these readings as needed in order to enhance your understanding of the course content.

    Here are the steps to follow to begin this course successfully:

    Review all the information contained in the links in the navigation area to the left.

    Click on the button for
    Week 1
    , and read the Introduction and Learning Outcomes for the week.

    Review the
    Resources
    ,
    Discussion
    , and
    Assignment
    areas for the week. Note that some weeks may have none or more than one of these types of activities. It is your responsibility to complete all the required activities. Use the
    Course Schedule
    as a guide NURS 6521 Syllabus.

    Follow this procedure for each week throughout the term

    Preferred Methods for Delivering Assignments

    Discussion postings
    : All postings need to be made in each week’s Discussion area or, when applicable, the Groups area of the course. Please do not send copies of postings to the Instructor or students via e-mail.

    Assignments
    : Be sure that all documents are saved and submitted as “.doc” files. You may also submit “.rtf” files, but formatting in these files may be lost, so “.doc” files are preferred. Assignments are named according to the week in which the Assignments is submitted NURS 6521 Syllabus. Directions for naming assignment files are given in each
    Assignments
    area. Please name your files as directed.

    E-Mail
    : All e-mail correspondence
    must
    contain in the subject line
    course number-XX – Your Name
    (XX is the section number) followed by a brief description of the subject. This subject line convention ensures that your e-mail will be easily identified and responded to in a timely manner.

    Policies on Late Assignments

    Discussion postings
    : Much of the learning in this class depends on participation in weekly Discussions; you are expected to contribute to them in the
    Discussion
    area. If you have problems and need to have a small extension (defined as 1–2 days), contact the Instructor and arrange this in advance. If you have not received permission from the Instructor, do not assume that an extension has been granted. No Discussion post will count for credit once the week has ended.

    Assignments
    : Assignments are due on the day of the week assigned in this syllabus.
    Failure to meet the deadline without prior approval from the instructor will result in zero points.

    Approval to submit an assignment late is at the sole discretion of the instructor and may be given only for certifiable reasons such as an illness. The instructor may require that you provide relevant documentation NURS 6521 Syllabus.

    If you have not received permission from the instructor, do not assume that an extension has been granted.

    Assignments must be submitted according to the instructions and must be in a format that your instructor can open and read.

    Failure to comply with submission instructions, to provide a document that your instructor can open and read.

    Technology issues are not valid reasons for missing deadlines.

    No Assignment will be accepted after the last day of the term (Week 8, Day 7) unless prior approval is obtained from the instructor.

    Keeping Your Coursework

    ou will have access to the course and your coursework from the course start date until 60 days after the course ends. After this time, you will no longer be able to access the course or related materials.
    For this reason, we strongly recommend that you retain copies of your completed assignments and any documents you wish to keep.
    The University is not responsible for lost or missing coursework NURS 6521 Syllabus.

    Course Evaluation

    At or near the end of the course, you will receive an e-mail inviting you to submit an online evaluation of the course and instruction. All submitted course evaluations are confidential, and only aggregate data and comments will be shared with the Instructor and Program Director. Your feedback is vitally important to Walden University in its efforts to continuously improve programs.

    Students With Disabilities

    Students in this course who have a disability that might prevent them from fully demonstrating their abilities should contact the director of disability services at
    disability@waldenu.edu
    or at 1-800-925-3368, ext. 312-1205 and +1-612-925-3368 or
    http://www.waldenu.edu/contact
    for international toll-free numbers as soon as possible to initiate disability verification and discuss accommodations that may be necessary to ensure full participation in the successful completion of course requirements NURS 6521 Syllabus.

    disability@waldenu.edu

    http://www.waldenu.edu/contact

    Classroom Participation

    In accordance with US Department of Education guidance regarding class participation, Walden University requires that all students submit their required Week 1 assignments within each course(s) during the first 7 calendar days of class. The first calendar day of class is the official start date of the course as posted on your myWalden academic page.

    Assignments submitted prior to the official start date will not count toward your participation.

    Financial Aid cannot be released without class participation as defined above.

    Students who have already taken, and successfully completed, at least
    one or more
    class(es) with Walden will be dropped
    ONLY
    from any class(es) in which they are
    not participating
    if they do not complete their assignments by the end of the 7
    th
    day.

    Students who
    are taking their first class with Walden,
    and do not complete their assignments by the end of the 7
    th
    day, will be administratively withdrawn from the university NURS 6521 Syllabus.

    If you have any questions about your assignments, or you are unable to complete your assignments, please contact your faculty member.

    Checklist

    The weekly course checklist below outlines the assignments due for the course.

    All assignments are due by
    11:59 p.m. Mountain Time (MT)
    on the day assigned (which is 1:59 a.m. Eastern Time (ET) the next day). The time stamp in the classroom will reflect Eastern Time (ET), regardless of your time zone. As long as your submission time stamp is no later than 1:59 a.m. Eastern Time (ET), you have submitted on time.

    To View the Calendar

    To view the Course Calendar:

    Course Calendar

     

    To View a Printable Course Schedule

    For full assignment details and directions, refer to each week of the course.

    Click on the
    NURS 6521 Course Schedule (PDF)
    link to access the Course Schedule.

    Document: NURS 6521: Course Schedule (PDF)

     

    Checklist

    Module

    Assignment

    Title

    Week 1

    Basic Pharmacotherapeutic Concepts

    Learning Resources

    Required Readings

    Optional Readings

    Discussion

    Pharmacokinetics and Pharmacodynamics

    Quiz

    Week 1 Quiz

    Week 2

    Ethical and Legal Aspects of Prescribing

    Learning Resources

    Required Readings

    Optional Readings

    Discussion

    Ethical and Legal Implications of Prescribing Drugs

    Assignment

    The Ethics and Legalities of Medication Error Disclosure

    Quiz

    Week 2 Quiz NURS 6521 Syllabus

    Week 3

    Cardiovascular System

    Learning Resources

    Required Readings

    Optional Readings

    Discussion

    Pharmacotherapy for Cardiovascular Disorders

    Quiz

    Week 3 Quiz

    Week 4

    Respiratory System

    Learning Resources

    Required Readings

    Optional Readings

    Discussion

    Pharmacotherapy for Respiratory Disorders

    Assignment

    Asthma and Stepwise Management

    Quiz

    Week 4 Quiz

    Week 5

    Neurological System NURS 6521 Syllabus

    Learning Resources

    Required Readings

    Optional Readings

    Discussion

    Pharmacotherapy for Neurological Disorders

    Quiz

    Week 5 Quiz

    Week 6

    Endocrine and Musculoskeletal System

    Learning Resources

    Required Readings

    Optional Readings

    Discussion

    Pharmacotherapy for Endocrine and Musculoskeletal Disorders

    Assignment

    Diabetes and Drug Treatments

    Quiz

    Week 6 Quiz

    Week 7

    Gastrointestinal and Hepatobiliary System

    Learning Resources

    Required Readings

    Optional Readings

    Discussion

    Pharmacotherapy for Gastrointestinal and Hepatobiliary Disorders

    Quiz

    Week 7 Quiz

    Week 8

    Infections

    Learning Resources

    Required Readings

    Optional Readings

    Discussion

    Drug Treatments for HIV/AIDS

    Assignment

    Antimicrobial Agents

    Quiz

    Week 8 Quiz

    Week 9

    Hematologic System

    Learning Resources

    Required Readings

    Optional Readings

    Discussion

    Pharmacotherapy for Hematologic Disorders

    Quiz

    Week 9 Quiz

    Week 10

    Women’s and Men’s Health

    Learning Resources

    Required Readings

    Optional Readings

    Discussion

    Hormone Replacement Therapy

    Assignment

    Cancer and Women’s and Men’s Health

    Quiz

    Week 10 Quiz

    Week 11

    Pediatrics

    Learning Resources

    Required Readings

    Optional Readings

    Discussion

    Off-Label Drug Use in Pediatrics

    Quiz

    Week 11 Quiz

    Bibliography

    The bibliography contains the references for all learning materials in the course. For your convenience, a link has been provided to download and save the bibliography. NURS 6521 Syllabus

    To access the Bibliography:

    NURS 6521 Bibliography (PDF)

    NURS 6521 Syllabus

  • NURS 6521 Walden University Quiz

    NURS 6521 Walden University Quiz

    Question 1

    1 out of 1 points

    A male patient with a diagnosis of relapsing-remitting multiple sclerosis is in the clinic to discuss with the nurse the possibility of self-administration of glatiramer. During the patient education session for self-administration, the nurse will emphasize

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    Response Feedback:

    Since administration of glatiramer is by subcutaneous injection only, the nurse will teach the patient to rotate injection sites. Appropriate sites for the patient would include the thigh, stomach, and upper arm.

    Question 2

    1 out of 1 points

    NURS 6521 Walden University Quiz

    A nurse is developing a care plan for a patient who has multiple sclerosis. An expected outcome for the patient who is receiving glatiramer would be a decrease in

     

    Response Feedback:

    Glatiramer should reduce the frequency of multiple sclerosis–related attacks and therefore decrease fatigue. Fatigue, weakness, spasticity, balance problems, bladder and bowel problems, numbness, vision loss, tremor, and vertigo are the most common symptoms of multiple sclerosis. Chest pain, breathing difficulties, and heart palpitations are all identified side effects of glatiramer and are not common manifestations of MS.

    Question 3

    1 out of 1 points

    A nurse is teaching a patient about his newly prescribed drug, colchicine, for gout. The nurse will instruct the patient to avoid which of the following foods?

     

    Response Feedback:

    High consumption of meat products and seafood increases the risk of hyperuricemia, which is the root cause of gout. Purine-rich vegetables do not increase the risk of hyperuricemia, and a high dairy intake is actually protective.

    Question 4

    1 out of 1 points

    NURS 6521 Walden University Quiz

    A patient with diabetes has had a cough for 1 week and has been prescribed a cough syrup (an expectorant). What special instructions should the nurse include in the patient teaching for this situation?

     

    Response Feedback:

    Special instructions need to be given to patients with diabetes when they are prescribed syrups. A diabetic patient needs to monitor glucose levels closely because syrups contain high levels of sugars, which can cause elevated glucose levels. Increased gastrointestinal tract infections are not directly related to diabetic patients taking cough syrups. Noting the time that a medication is taken and good hand-washing are always important, but are not specific considerations for a diabetic patient taking cough syrup.

    Question 5

    1 out of 1 points

    A nurse is instructing a patient in the administration of regular insulin by the subcutaneous route. Which of the following strategies would the nurse suggest if the goal is to promote absorption of the regular insulin?

     

    Response Feedback:

    To promote the absorption of regular insulin, one anatomic area should be selected for subcutaneous injections. Serial locations within that anatomic area are then chosen to rotate the exact injection site. Injection sites should not be rotated by using different anatomic areas each day, because this would substantially change the absorption of the insulin and the patient’s blood glucose levels. Using one injection site regularly may lead to lipodystrophy. Regular insulin is administered about 30 to 60 minutes before eating a meal, not after. NURS 6521 Walden University Quiz

    Question 6

    1 out of 1 points

    A 66-year-old woman has experienced a significant decline in her quality of life as a result of worsening rheumatoid arthritis. Her physician has prescribed etanercept and the nurse is responsible for facilitating this new aspect of the patient’s drug regimen. This will involve the administration of

     

    Response Feedback:

    Etanercept is a weekly subcutaneous injection.

    Question 7

    1 out of 1 points

    A patient is taking gabapentin (Neurontin) for spasticity associated with multiple sclerosis. Which of the following should be the priority for monitoring?

     

    Response Feedback:

    Gabapentin is not metabolized and is excreted unchanged in the urine. Therefore, it is important to monitor renal function. Hepatic, cardiac, and respiratory functions are not compromised with this drug.

    Question 8

    1 out of 1 points

    A nurse is working with a 57-year-old man who is a former intravenous drug abuser. He has been prescribed a weekly dosage of methotrexate for his rheumatoid arthritis. Which of the following will the nurse include in her teaching plan for this patient?

     

    Response Feedback:

    Use of illicit drugs as well as an age-related decrease in renal function may have predisposed the patient to nephrotoxicity. Therefore, it is most important for the nurse to advise the patient to drink enough water to decrease the risk for nephrotoxicity when taking methotrexate. Avoiding red meat or taking the tablets before bedtime does not help reduce the risk of nephrotoxicity.

    Question 9

    1 out of 1 points

    A 70-year-old woman who is on long-term ibuprofen therapy for osteoarthritis has returned to the clinic for her regular 6-month visit. In the last couple of months, she has been having increasing periods of abdominal pain. The nurse suspects that this pain may be related to

     

    Response Feedback:

    During long-term ibuprofen therapy, especially in patients older than 60 years, the nurse needs to closely monitor for peptic ulcer disease or gastritis that can lead to gastrointestinal bleeding or even bowel perforation. These events can occur at any time, with or without warning. Ibuprofen may also cause excessive or abnormal bleeding, especially in patients with anemia, but it is not known to cause anemia. Interstitial nephritis is one of the less common renal toxicities associated with ibuprofen as is constipation. NURS 6521 Walden University Quiz

    Question 10

    1 out of 1 points

    A 40-year-old woman with a diagnosis of fibromyalgia has been prescribed cyclobenzaprine (Flexeril) as an adjunct to her existing drug regimen. What nursing diagnosis should the nurse prioritize when updating the nursing care plan for this patient?

     

    Response Feedback:

    The CNS depression that is associated with the use of cyclobenzaprine constitutes a risk for injury. The anticholinergic effects of the drug constitute a risk for constipation, not diarrhea. Nutrition and swallowing are not typically affected by the use of cyclobenzaprine.

    Question 11

    1 out of 1 points

    A patient receives 25 units of NPH insulin at 7.AM. At what time of day should the nurse advise the patient to be most alert for a potential hypoglycemic reaction?

     

    Response Feedback:

    After an early morning dose of NPH insulin, the patient should be alert for a possible hypoglycemic reaction during mid- to late-afternoon. The lengthy peak action time produces additional risks for hypoglycemic reactions.

    Question 12

    1 out of 1 points

    A 33-year-old man has developed acute gouty arthritis. He has been prescribed colchicine. When developing a care plan for this patient, which factor will be most important for the nurse to consider?

     

    Response Feedback:

    The nurse must consider the patient’s dietary habits because foods high in purines increase uric acid concentrations in the blood, making a gouty attack more likely. Assessing the patient’s work environment, fluid intake, and ethnicity are not as important as assessing his dietary habits.

    Question 13

    1 out of 1 points

    A nurse is caring for a patient who has been diagnosed with hypothyroidism. Levothyroxine (Synthroid) has been prescribed. Before the drug therapy is started, the nurse will assess for which of the following?

    NURS 6521 Walden University Quiz

    Response Feedback:

    If the patient is taking anticoagulant drugs, there is a risk of a drug–drug interaction with levothyroxine that can result in an increased risk of bleeding. Therefore, the nurse should assess the patient’s medical record and drug history. Bleeding times such as INR, PR, and PTT should be closely monitored if it is necessary for the two drugs to be given together. There is no evidence that an allergy to seafood, the patient’s age, or hirsutism, which is excessive hair growth, would need to be assessed in this case.

    Question 14

    1 out of 1 points

    The nurse is conducting a medication reconciliation of a new resident of a long-term care facility. The nurse notes that the resident takes allopurinol on a daily basis for the treatment of gout. What is the primary purpose of this drug?

     

    Response Feedback:

    Uricosuric drugs such as allopurinol help to balance urate levels and thus prevent gout attacks. They do not influence the remodeling of synovial membrane, provide analgesia, or affect the metabolism of purines. NURS 6521 Walden University Quiz

    Question 15

    1 out of 1 points

    A patient in need of myocardial infarction prophylaxis has been prescribed sulfinpyrazone for gout. Which of the following will the nurse monitor the patient most closely for?

     

    Response Feedback:

    Since sulfinpyrazone inhibits antiplatelet action, it is important for the nurse to monitor the patient for signs of bleeding. It is also important to avoid administration of sulfinpyrazone with other drugs such as salicylates and anticoagulants (warfarin) that affect platelet aggregation. The drug does not pose a risk of hypothermia, hypotension, or renal dysfunction.

    Question 16

    1 out of 1 points

    A 49-year-old woman has been diagnosed with myalgia. The physician has recommended aspirin. The patient is concerned that the aspirin will upset her stomach. The nurse will encourage the patient to

     

    Response Feedback:

    Taking aspirin with milk or food minimizes the stomach upset because it buffers the stomach wall from direct contact with the medication, decreasing gastric distress. Chewable tablets can be chewed before swallowing or crushed and then advised to be taken with food or mixed in a drink. Swallowed whole, extended-release tablets are enteric coated to delay release of the aspirin, which again buffers the stomach wall from the medication, decreasing gastric distress. Nonchewable tablets should be swallowed whole and should never be advised to be crushed or chewed.

    Question 17

    1 out of 1 points

    NURS 6521 Walden University Quiz

    A nurse is instructing a patient who was recently diagnosed with multiple sclerosis about dantrolene (Dantrium). The patient is a 38-year-old-male and the foreman for a construction company. In order to minimize one important adverse effect of the drug, the nurse will give the patient which of the following instructions?

     

    Response Feedback:

    The nurse will need to caution the patient about the adverse effect of photosensitivity, especially considering his work.
     
    He should be advised to wear protective clothing and sunglasses and to use sunscreen whenever he is outside on the job site. A complete blood cell count should be done before therapy begins but would not be needed again unless indicated. A nurse must check with the prescriber before advising a patient to decrease a drug dosage. A diet high in protein is not necessary with this drug.

    Question 18

    1 out of 1 points

    A nurse is assessing a patient who has come to the emergency department complaining of back spasms. The patient states that he has a history of opioid addiction and does not want to take any drug that “puts me at risk of becoming physically dependent.” Which of the following medications would the nurse question, if ordered?

    NURS 6521 Walden University Quiz

    Response Feedback:

    The nurse would be concerned if the physician ordered cyclobenzaprine because long-term use of this drug may result in physical dependence. The other drugs listed are not associated with physical dependence.

    Question 19

    1 out of 1 points

    A female patient with a diagnosis of type 1 diabetes mellitus has been experiencing increasing neuropathic pain in recent months, a symptom that has not responded appreciably to conventional analgesics. The patient’s care provider has begun treatment with gabapentin (Neurontin). How is the addition of this drug likely to influence the management of the patient’s existing drug regimen?

     

    Response Feedback:

    Gabapentin is unusual in that it does not interact with other drugs and does not alter the serum concentrations of other anticonvulsants. Consequently, it is unnecessary to modify the patient’s existing drug regimen. Regular assessment of renal function is necessary in patients with diabetes, but this is not a consequence of the use of gabapentin.

    Question 20

    1 out of 1 points

    A nurse will instruct a patient taking allopurinol to take each dose

    NURS 6521 Walden University Quiz

    Response Feedback:

    The nurse should teach the patient to take each dose after a meal to decrease the potential for nausea and vomiting. Taking this medicine at night, in the morning, or before a meal would not help decrease the GI symptoms associated with this drug.

    Question 21

    1 out of 1 points

    A 65-year-old woman has an advanced form of rheumatoid arthritis. Her treatment includes a regular dosage of methotrexate. The nurse will advise her to take which of the following vitamin supplements while taking the drug?

     

    Response Feedback:

    Taking vitamin B every day will help decrease the potential for adverse effects of methotrexate. This drug is given cautiously to very young and elderly patients, because these patients’ livers and kidneys cannot adequately clear the drug. Vitamin C is contraindicated with most antiarthritic and antigout drugs because it decreases the renal excretion of drugs. Supplements of vitamin A or D would not be necessary.

    Question 22

    1 out of 1 points

    A 32-year-old female patient is taking tizanidine (Zanaflex) for spasticity related to her multiple sclerosis. The nurse will inform the patient and her husband that the adverse effect that poses the greatest safety risk to the patient is

     

    Response Feedback:

    Tizanidine (Zanaflex) has been associated with hypotension, which could be a safety risk, especially if the patient is also taking an antihypertensive drug. Constipation, dry mouth, and fatigue are common adverse effects that do not pose a safety risk.

    Question 23

    1 out of 1 points

    A nurse has been invited to speak to a support group for persons with movement disorders and their families. Which of the following statements by the nurse addresses the chronic nature of these diseases and the relevant drug therapies?

    NURS 6521 Walden University Quiz

    Response Feedback:

    It is most important that patients and their families know that movement disorders are chronic, that there is no cure, and that drug therapy only serves to help decrease the severity of the symptoms. Symptoms are not normally eliminated completely. Culture must be considered because of catecholamine-O-methyltransferase (COMT), which affects the absorption of levodopa in the body. Some of the drugs used to treat movement disorders can pose a risk of causing renal or hepatic dysfunction, but not all.

    Question 24

    1 out of 1 points

    A 34-year-old male patient is prescribed methimazole (MMI). The nurse will advise him to report which of the following immediately?

     

    Response Feedback:

    The nurse should ask the patient to report immediately if he notices decreased cardiac rate, intolerance to cold, or weight gain. These are indications of hypothyroidism resulting from antithyroid therapy, and if the medication is continued unchanged, insidious goitrogenic hypothyroidism may occur. Vertigo, drowsiness, loss of appetite, and epigastric distress are possible adverse effects of the therapy but would not present an immediate risk to the patient’s health.

    Question 25

    1 out of 1 points

    A clinic nurse is following a 9-year-old boy who is taking somatropin. Which of the following will the nurse monitor periodically?

     

    Response Feedback:

    Somatropin is used for the long-term treatment of pediatric patients who have growth failure due to an inadequate secretion of endogenous growth hormone; therefore, the nurse should check the patient’s height. If the patient’s growth rate does not exceed the pretreatment rate by at least 2 cm per year, nonadherence to therapy, antibody formation, malnutrition, or hypothyroidism may be considered as possible causes. Somatropin would not significantly affect antidiuretic hormone (ADH) levels, or cause dehydration or water retention. NURS 6521 Walden University Quiz.

    Question 26

    1 out of 1 points

    Which of the following would be the most important safety-related instruction for a nurse to give to a patient taking baclofen (Lioresal)?

     

    Response Feedback:

    In a patient experiencing spasticity, the nurse should advise the patient to stop drinking alcohol. Alcohol consumption may increase the adverse effect of sedation, causing sleepiness, dizziness, and blurred vision. The patient should not drive or walk after taking the drug; he should learn to self-administer the drug; and constipation is a concern. However, the most important safety concern is to avoid alcohol.

    Question 27

    1 out of 1 points

    A nurse will monitor which of the following when assigned to a patient taking allopurinol for chronic gout who visits the clinic every 2 months?

     

    Response Feedback:

    The most common adverse effects of allopurinol include pruritus, maculopapular rash, nausea and vomiting, elevated liver function tests, and acute gout symptoms. Blood sugar levels, blood pressure, and body temperature are not associated with adverse effects of allopurinol.

    Question 28

    1 out of 1 points

    A patient with type 1 diabetes has been admitted to the hospital for orthopedic surgery and the care team anticipates some disruptions to the patient’s blood glucose levels in the days following surgery. Which of the following insulin regimens is most likely to achieve adequate glycemic control?

     

    Response Feedback:

    Subcutaneous insulin therapy for type 1 diabetes frequently consists of daily injections of mixtures of short-acting regular insulin with intermediate-acting insulins; multiple doses of regular insulin before each meal in association with one or two daily doses of long-acting insulin may also be used. Frequent, fixed doses of rapid-acting or intermediate-acting insulin may result in unsafe blood sugar levels. NURS 6521 Walden University Quiz.

    Question 29

    0 out of 1 points

    To minimize the risk of adverse effects of glucagon when given to an unconscious diabetic patient, as the patient regains consciousness, the nurse should

     

    Response Feedback:

    While it is important to monitor a patient for nausea and vomiting and help him or her into a more comfortable position, it is most important to administer supplemental carbohydrates as soon as the patient becomes conscious. Administering supplemental carbohydrates serves to restore liver glycogen and prevent secondary hypoglycemia. Calcium supplements are not necessary in this situation.

    Question 30

    1 out of 1 points

    Following an assessment by her primary care provider, a 70-year-old resident of an assisted living facility has begun taking daily oral doses of levothyroxine. Which of the following assessment findings should prompt the nurse to withhold a scheduled dose of levothyroxine?

     

    Response Feedback:

    If the pulse rate is greater than 100 bpm, it is necessary to withhold a levothyroxine dose in an older adult. Anorexia, recent vaccination, and recent falls do not necessary indicate a need to withhold this medication.

  • Dementia Essay – NURS 6521 – Week 5 Discussion

    Dementia Essay – NURS 6521 – Week 5 Discussion

    Dementia

    Dementia is a general term for a decline in mental ability severe enough to interfere with daily life (Alzheimer’s Association, 2018). Memory loss is an example (Alzheimer’s Association, 2018). Alzheimer’s is the most common type of dementia (Alzheimer’s Association, 2018). Though most symptoms of dementia vary they include memory loss, communication and language impairment, ability to focus and pay attention, reasoning and judgment impairment, and visual perception (National Institute on Aging, 2018). The multiple psychological changes range from anxiety, depression, personality changes, inappropriate behavior, agitation, hallucinations, and paranoia (Mayo Clinic, 2017).

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    Dementia is caused by damage to the brain cells through excess alcohol use, medication side effects, depression, thyroid problems, trauma to head, stroke, and vitamin deficiencies (Alzheimer’s Association, 2018). There is no one test used to diagnose dementia, so the use of an extensive medical history including familial history, physical examination; changes in how the patients’ think, function, and behave are all used to help make this diagnosis. The progressive types of dementias are Alzheimer’s disease (AD), vascular, Lewy body, frontotemporal, and mixed (Mayo Clinic, 2017). Other disorders that are linked to dementia are Huntington’s, Parkinson’s, and Creutzfeldt-Jakob (Mayo Clinic, 2017). Dementia Essay – NURS 6521 – Week 5 Discussion.

    Pharmacotherapy for Dementia

    The main goal for the treatment of dementia is to improve the patient’s quality of life and prolong the disease process as long as possible. According to Arcangelo and Peterson (2017) there are several possible medications that patients could be on that could cause reversible effects of dementia that include anticholinergics, antipsychotics, benzodiazepines, and histamine blockers. To treat the disease itself, one would prescribe medications such as cholinesterase inhibitors and memantine (Arcangelo & Peterson, 2017). Some of the cholinesterase inhibitors include Aricept, Exelon, and Razadyne (Arcangelo & Peterson, 2017). When used in conjunction, the cholinesterase inhibitors and memantine help to prolong the disease as long as possible thereby giving the patient greater quality of life and functionality.

    It is currently unknown how long this treatment will continue to be of benefit to these patients, however once the disease reaches it’s inevitable conclusion most prescribers will remove the medications due to lack of beneficial therapeutics and cost of maintenance (Arcangelo & Peterson, 2017). The cholinesterase inhibitors have been shown to slow the progression of AD (Arcangelo & Peterson, 2017). These medications have also had positive effects on the noncognitive or behavioral symptoms of AD (Arcangelo & Peterson, 2017). They have been shown to reduce apathy, psychosis, anxiety, depression, and agitation (Arcangelo & Peterson, 2017). Dementia Essay – NURS 6521 – Week 5 Discussion.

    Dementia and Age

    Senior citizens are most affected by this disease process, but it can afflict those that are younger as well. Being elderly down not predispose one to this disease process, however there are risk factors that cannot be changed such as family history, Down Syndrome, age, and mild cognitive impairments. Risk factors that can be changed to either lessen the chances of acquiring the disease or stop it completely include alcohol use, depression, diabetes, cardiovascular risk factors, smoking, and sleep apnea.

    In order to reduce any side effects, the APRN can include the family in all of the teaching that is done, advise them to monitor all medication administration in order to maintain compliance, and to advise them that at some point further care will need to be addressed for patient functionality and activities of daily living. Also, the elderly can be very sensitive to medications so proper dosing will need to be taken into account in order to avoid hypersensitivity. To avoid this, the prescriber should begin treating at the lowest doses and working up from that point.

     

    References

    Alzheimer’s Association. (2018). What is dementia. Retrieved June 27, 2018 from
    https://www.alz.org/alzheimers-dementia/what-is-dementia

    Mayo Clinic. (2017). Dementia. Retrieved June 27, 2018 from
    https://www.mayoclinic.org/diseases-conditions/dementia/symptoms-causes/syc-20352013

    National Institute on aging. (2018). What is dementia. Retrieved June 27, 2018 from
    https://www.nia.nih.gov/health/what-dementia

     

    I enjoyed reading your post this week and liked what you had to say on migraines and gender. The link between hormones and migraine has uncovered new details about how fluctuating estrogen levels – and the life stages when women tend to experience them – could increase their vulnerability to migraine attacks (American Migraine Foundation, 2018). Furthermore, of the more than 38 million Americans who experience migraine headaches, 28 million are women. Dementia Essay – NURS 6521 – Week 5 Discussion. Compared to men, women also experience more frequent and severe migraines and don’t respond as well to drug treatments (Science Daily, 2018). My mother-in-law suffers badly from migraines. As she has gotten older, the migraines have become fewer, which suggests there may very well be a link between hormones and migraines, however I find it an extra kick in the gut that women also don’t respond as well to medications that are made to help with this dilemma.

    References

    American Migraine Foundation. (2018). Understanding the migraine gender gap. Retrieved June 29, 2018 from
    https://americanmigrainefoundation.org/2017/09/21/understanding-migraine-gender-gap/

    Science Daily. (2018). Potential source of gender differences in migraines. Retrieved June 29, 2018 from
    https://www.sciencedaily.com/releases/2018/04/180423085434.htm

     

    I enjoyed your post this week on epilepsy and age. The Epilepsy Foundation (2018) state after age 55, the rate of new cases of epilepsy starts to increase, as people develop strokes, brain tumors, or Alzheimer’s disease, which all can cause epilepsy. Furthermore, the Centers for Disease Control and Prevention (CDC) (2018) reports: About 3 million US adults aged 18 years or older have active epilepsy.
     
    Nearly 1 million of those adults are aged 55 or older. With our elderly living longer, there will no doubt be more and more patients who fall victim to this disease process. What are your thoughts on this possibility? Dementia Essay – NURS 6521 – Week 5 Discussion.

    References

    Centers for Disease Control and Prevention. (2018). Epilepsy and seizures in older adults. Retrieved June 30, 2018 from
    https://www.cdc.gov/features/epilepsy-older-adults/index.html

    Epilepsy Foundation. (2018). Who gets epilepsy. Retrieved June 30, 2018 from
    https://www.epilepsy.com/learn/about-epilepsy-basics/who-gets-epilepsy

    Dementia Essay – NURS 6521 – Week 5 Discussion

  • Nurs 6521 Pharm Week 7 Discussion – Pharmacotherapy for Gastrointestinal and Hepatobiliary Disorders

    Nurs 6521 Pharm Week 7 Discussion – Pharmacotherapy for Gastrointestinal and Hepatobiliary Disorders

    Pharmacotherapy for Gastrointestinal and Hepatobiliary Disorders

    Gastrointestinal (GI) and hepatobiliary disorders affect the structure and function of the GI tract. Many of these disorders often have similar symptoms such as abdominal pain, cramping, constipation, nausea, bloating, and fatigue. Since multiple disorders can be tied to the same symptoms, it is important for advanced practice nurses to carefully evaluate patients and prescribe treatment that targets the cause rather than the symptom. Once the underlying cause is identified, an appropriate drug therapy plan can be recommended based on medical history and individual patient factors. In this Discussion, you examine a case study of a patient who presents with symptoms of a possible GI/hepatobiliary disorder, and you design an appropriate drug therapy plan. Nurs 6521 Pharm Week 7 Discussion – Pharmacotherapy for Gastrointestinal and Hepatobiliary Disorders.

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    Consider the following case study:

    Patient HL comes into the clinic with the following symptoms: nausea, vomiting, and diarrhea. The patient has a history of drug abuse and possible Hepatitis C. HL is currently taking the following prescription drugs:

    Synthroid 100 mcg daily

    Nifedipine 30 mg daily

    Prednisone 10 mg daily

    To prepare:

    ·        Review this week’s media presentation on pharmacology for the gastrointestinal system.

    ·        Review the provided case study. Reflect on the patient’s symptoms, medical history, and drugs currently prescribed. Nurs 6521 Pharm Week 7 Discussion – Pharmacotherapy for Gastrointestinal and Hepatobiliary Disorders.

    ·        Think about a possible diagnosis for the patient. Consider whether the patient has a disorder related to the gastrointestinal and hepatobiliary system or whether the symptoms are the result of a disorder from another system or other factors such as pregnancy, drugs, or a psychological disorder.

    ·        Consider an appropriate drug therapy plan based on the patient’s history, diagnosis, and drugs currently prescribed.

    Post 1 page page APA format  

     
    an explanation of your diagnosis for the patient including your rationale for the diagnosis.

    Then, describe an appropriate drug therapy plan based on the patient’s history, diagnosis, and drugs currently prescribed.
    (Note this is a pharmacology class make sure medicine is appropriate and will work with pt’s current med list)
    Nurs 6521 Pharm Week 7 Discussion – Pharmacotherapy for Gastrointestinal and Hepatobiliary Disorders.

     

    Readings

    ·        Arcangelo, V. P., & Peterson, A. M. (Eds.). (2013). 
    Pharmacotherapeutics for advanced practice: A practical approach
     (3rd ed.). Ambler, PA: Lippincott Williams & Wilkins.

    o   Chapter 28, “Nausea and Vomiting” (pp. 392–409)

    This chapter focuses on the etiology of nausea and vomiting, as well as body systems that impact or trigger nausea and vomiting. It also covers various drugs used to treat nausea and vomiting including the process of selecting, administering, and managing drug therapy for patients.

    o   Chapter 29, “Gastroesophageal Reflux Disease and Peptic Ulcer Disease” (pp. 410–423)

    This chapter begins with an overview of risk factors, symptoms, and clinical stages of gastroesophageal reflux disease (GERD). It then examines drugs used to treat GERD and peptic ulcer disease (PUD), including proper dosages, possible adverse reactions, contraindications, and special considerations. Nurs 6521 Pharm Week 7 Discussion – Pharmacotherapy for Gastrointestinal and Hepatobiliary Disorders.

    o   Chapter 30, “Constipation, Diarrhea, and Irritable Bowel Syndrome” (pp. 424–453)

    This chapter begins by exploring disorders associated with constipation and diarrhea, as well as drugs used in treatment. It also covers the pathophysiology of irritable bowel syndrome and related drug therapies.

    o   Chapter 31, “Inflammatory Bowel Disease” (pp. 454–471)

    This chapter examines the causes, pathophysiology, and diagnostic criteria of inflammatory bowel disease (IBD), Crohn’s disease, and ulcerative colitis. It also identifies drugs used to treat IBD, including proper dosage, adverse reactions, and special considerations.

    ·        Starr, S., & Raines, D. (2011). Cirrhosis: Diagnosis, management, and prevention. 
    American Family Physician
    , 
    84
    (12), 1353–1359.

    Retrieved from the Walden Library databases.

    This article examines the clinical presentation, pathophysiology, diagnosis, management, and prevention of cirrhosis. It also provides methods for managing complications of cirrhosis.

    ·        Drugs.com. (2012). Retrieved from 
    http://www.drugs.com/

    This website presents a comprehensive review of prescription and over-the-counter drugs including information on common uses and potential side effects. It also provides updates relating to new drugs on the market, support from health professionals, and a drug-drug interactions checker. Nurs 6521 Pharm Week 7 Discussion – Pharmacotherapy for Gastrointestinal and Hepatobiliary Disorders.

  • NURS 6521 Advanced Pharmacology – Week 7 – Quiz

    NURS 6521 Advanced Pharmacology – Week 7 – Quiz

    Attempt Score

    34 out of 35 points

    Time Elapsed

    1 hour, 8 minutes out of 1 hour and 30 minutes

    Instructions

    Please answer each question below and click 
    Submit
     when you have completed the Quiz.

    Results Displayed

    Feedback

    Question 1

    1 out of 1 points

    A woman with numerous chronic health problems has been diagnosed with a benign gastric ulcer has begun treatment with ranitidine (Zantac). Which of the following teaching points should the nurse provide to this patient?

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    Response Feedback:

    Smoking reverses the drug-induced inhibition of nocturnal gastric acid production and hinders ulcer healing. Cigarette smoking also is related closely to ulcer recurrence. Ranitidine should not be taken simultaneously with antacids and it does not eradicate 
    H. pylori
    . It is not necessary to eat multiple small meals during the day. NURS 6521 Advanced Pharmacology – Week 7 – Quiz.

    Question 2

    1 out of 1 points

    A teenage boy has undergone a diagnostic workup following several months of persistent, bloody diarrhea that appears to lack an infectious etiology. The boy has also experienced intermittent abdominal pain and has lost almost 15 pounds this year. Which of the following medications is most likely to treat this boy’s diagnosis?

     

    Response Feedback:

    This patient’s history and presentation are strongly suggestive of ulcerative colitis, a disease for which mesalamine is an approved treatment. Lubiprostone is used for the treatment of constipation and docusate is a stool softener. Bismuth subsalicylate is an antidiarrheal but is not effective in the management of ulcerative colitis.

    Question 3

    1 out of 1 points

    A nurse is aware that diphenoxylate HCl with atropine sulfate is an effective adjunct in the treatment of diarrhea. For which of the following patients could the administration of this drug be potentially harmful? NURS 6521 Advanced Pharmacology – Week 7 – Quiz

     

    Response Feedback:

    Use of diphenoxylate HCl is contraindicated for diarrhea caused by GI organisms that penetrate the gastric mucosa (such as 
    C. difficile
    ) because the drug slows peristalsis and may aggravate and prolong the diarrhea. Diarrhea associated with stress, influenza, and tube feeding can be safely treated with the drug in most cases.

    Question 4

    1 out of 1 points

    A nurse is planning care for a 59-year-old woman who is on ranitidine therapy. The nurse is concerned for the patient’s safety. Which of the following would be an appropriate nursing diagnosis?

     

    Response Feedback:

    The appropriate nursing diagnosis related to safety would be Risk for Injury related to drug-induced somnolence, dizziness, confusion, or hallucinations. Diarrhea related to adverse effects of drug therapy and Acute Pain related to adverse drug effects, headache are appropriate nursing diagnosis for a patient taking ranitidine, but are not related to safety. Potential Complication: Electrolyte Imbalance related to hypophosphatemia, secondary to drug therapy would be appropriate for a patient taking an aluminum hydroxide with magnesium hydroxide antacid (Maalox, Mylanta). NURS 6521 Advanced Pharmacology – Week 7 – Quiz.

    Question 5

    1 out of 1 points

    It is determined that a patient, who is in a hepatic coma, needs a laxative. Lactulose is prescribed. Which of the following should the nurse monitor to assess the efficacy of the lactulose therapy?

     

    Response Feedback:

    Similar to the saline laxative magnesium hydroxide, lactulose pulls water into the colon. Unlike magnesium hydroxide, lactulose is a synthetic disaccharide of lactose. In the colon, bacteria metabolize lactulose into acids and carbon dioxide, increasing the oncotic pressure in the colon and drawing water into the stool. The acids formed also draw ammonia into the stool. Therefore, lactulose is used not only to treat constipation but also to decrease blood ammonia levels in patients in hepatic coma and those with hepatic encephalopathy. The other factors, although significant, would not indicate the efficacy of the lactulose therapy as accurately as blood ammonia levels. NURS 6521 Advanced Pharmacology – Week 7 – Quiz.

    Question 6

    0 out of 1 points

    A nurse is providing discharge instructions to a patient who will be taking fludrocortisone at home. The nurse will encourage the patient to eat a diet that is

     

    Response Feedback:

    The patient should avoid foods that are high in sodium and eat foods that are high in potassium. The patient should eat foods rich in proteins because long-term fludrocortisone therapy promotes the deposition of liver glycogen and induces a negative nitrogen balance. NURS 6521 Advanced Pharmacology – Week 7 – Quiz. Iron-rich food is not typically shown to have therapeutic or adverse effects of fludrocortisone; therefore, it is more important to instruct the patient to avoid high-sodium foods and to eat potassium-rich ones.

    Question 7

    1 out of 1 points

    A woman with an inflammatory skin disorder has begun taking prednisone in an effort to control the signs and symptoms of her disease. The nurse who is providing care for this patient should prioritize which of the following potential nursing diagnoses in the organization of the patient’s care?

     

    Response Feedback:

    Treatment with glucocorticoids such as prednisone is associated with numerous adverse effects, including the risk for excess fluid volume. Constipation and impaired gas exchange are not among the most common adverse effects and CNS effects are normally limited to anxiety, mood swings, and insomnia rather than acute confusion.

    Question 8

    1 out of 1 points

    A 42-year-old man is being treated for a peptic ulcer with ranitidine (Zantac) taken PO at bedtime. Even though few adverse effects are associated with this drug, one common adverse effect that can be severe is

     

    Response Feedback:

    Even though ranitidine generally is well tolerated, headache is a common adverse effect that can be severe. The nurse will encourage the patient to adjust lights or temperature and avoid noise if headaches occur and to contact his physician if the headache becomes intolerable. Irritability, dry mouth, and heart palpitations are not associated with this drug. NURS 6521 Advanced Pharmacology – Week 7 – Quiz.

    Question 9

    1 out of 1 points

    A 48-year-old woman who works as an office manager is prescribed metoclopramide (Reglan) for diabetic gastroparesis. The nurse will be sure to assess the patient for

     

    Response Feedback:

    Depression, from mild to severe, including suicidal ideation, has occurred in patients with and without a history of depression who take metoclopramide. Use caution in administering metoclopramide to patients with a history of depression. The nurse should assess the patient for signs of depression and monitor behavior as long as the patient is on the therapy. If the patient has been depressed or is depressed, metoclopramide therapy should be given only if the benefits of the drug outweigh the potential risks from depression. Tachycardia, hypotension, and anemia are not associated with metoclopramide.

    Question 10

    1 out of 1 points

    A 60-year-old man has scheduled a follow-up appointment with his primary care provider stating that the omeprazole (Prilosec) which he was recently prescribed is ineffective. The patient states, “I take it as soon as I feel heartburn coming on, but it doesn’t seem to help at all.” How should the nurse best respond to this patient’s statement?

     

    Response Feedback:

    Optimal efficacy requires that omeprazole is taken daily, not just when the patient is symptomatic. A lack of immediate symptomatic relief does not necessarily indicate that the drug is ineffective.

    Question 11

    1 out of 1 points

    A patient who takes aluminum hydroxide with magnesium hydroxide (Mylanta) frequently for upset stomach, heartburn, and sour stomach is seen regularly in the clinic. The nurse should assess which of the following?

     

    Response Feedback:

    The nurse should monitor the patient’s serum phosphate level because aluminum binds with phosphate. This can lower phosphate levels and cause an electrolyte imbalance. Blood glucose, urine specific gravity, and aspartate transaminase levels are not affected by this drug combination.

    Question 12

    1 out of 1 points

    Following an endoscopy, a 66-year-old man has been diagnosed with a duodenal ulcer resulting from 
    Helicobacter pylori
     infection. Which of the following medications will likely be used in an attempt to eradicate the patient’s 
    H. pylori 
    infection? (Select all that apply.)

     

    Response Feedback:

    Classic quadruple therapy for 
    H. pylori 
    eradication (bismuth, a PPI, 1,500 mg of metronidazole, and 1,500 mg of tetracycline) is highly effective and is frequently the regimen of choice. A newer sequential therapy (PPI plus amoxicillin followed by a PPI plus clarithromycin plus metronidazole) has been proposed and is expected to replace legacy therapy. Both regimens include PPIs and antibiotics and exclude aluminum hydroxide, ondansetron, and cisapride.

    Question 13

    1 out of 1 points NURS 6521 Advanced Pharmacology – Week 7 – Quiz

    A 33-year-old woman has irritable bowel syndrome (IBS). The physician has prescribed simethicone (Mylicon) for her discomfort. Which of the following will the nurse monitor most closely during the patient’s drug therapy?

     

    Response Feedback:

    The nurse needs to closely monitor the patient for increased abdominal pain, nausea, fever, and vomiting. These symptoms are not indicative of excessive flatus, for which simethicone is prescribed, but indicate that the patient needs urgent medical attention for another condition. There is no risk for drug toxicity, anorexia, or increased urine output.

    Question 14

    1 out of 1 points

    A 58-year-old man is prescribed dicyclomine (Bentyl) for irritable bowel syndrome. In which of the following conditions is dicyclomine therapy contraindicated?

     

    Response Feedback:

    Dicyclomine is contraindicated for patients with myasthenia gravis, glaucoma, GI tract obstruction, paralytic ileus, and toxic megacolon. The drug is not contraindicated for patients with hypertension, diabetes mellitus, and rheumatoid arthritis.

    Question 15

    1 out of 1 points

    A 73-year-old woman has scheduled an appointment with her nurse practitioner to discuss her recurrent constipation. The woman states that she experiences constipation despite the fact that she takes docusate on a daily basis and performs cleansing enemas several times weekly. How should the nurse best respond to this patient’s statements?

     

    Response Feedback:

    Chronic use of laxatives may lead to dependency on the laxative to expel a bowel movement. This pattern is especially common among older adults. This phenomenon is more likely than a pathological condition. It would be inappropriate to suggest more (or different) laxatives.

    Question 16

    1 out of 1 points

    A 29-year-old female patient has been prescribed orlistat (Xenical) for morbid obesity. The nurse is providing patient education concerning the drug. An important instruction to the patient would be to

     

    Response Feedback:

    The nurse should instruct the patient to omit the orlistat (Xenical) for any meal that does not contain fat. The nurse should also instruct the patient to limit dietary intake of fat to 30% of calories. This drug is a reversible lipase inhibitor. By inhibiting the action of lipase, it decreases the absorption of dietary fats. The patient would be advised to take a multivitamin that contains fat-soluble vitamins to prevent imbalances from drug therapy. The administration of orlistat and multivitamins should be separated by 2 hours. Dietary protein does not interfere with the action of orlistat.

    Question 17

    1 out of 1 points NURS 6521 Advanced Pharmacology – Week 7 – Quiz

    An adult patient who has been diagnosed with a rectal tumor is scheduled to begin treatment with cisplatin. The nurse has conducted patient teaching about the possibility of nausea and vomiting. In order to reduce the patient’s risk of severe nausea, the nurse should

     

    Response Feedback:

    Antiemetics should be administered proactively rather than waiting until the patient’s nausea becomes unbearable. A combination approach is often effective. A low-residue diet is unnecessary and withholding food does not necessarily reduce nausea. NURS 6521 Advanced Pharmacology – Week 7 – Quiz

  • NURS-6521 Advanced Pharmacology – Week 5 – Quiz

    NURS-6521 Advanced Pharmacology – Week 5 – Quiz

    10/1/2018 Review Test Submission: Week 5 – Quiz – NURS-6521N-18,…

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    NURS-6521N-18,Advanced Pharmacology.2018 Fall Quarter 08/27-11/18-PT27

    Quizzes Review Test Submission: Week 5 – Quiz

    Review Test Submission: Week 5 –

    Quiz

    User Mina Song

    Course NURS-6521N-18,Advanced Pharmacology.2018 Fall Quarter 08/27-

    11/18-PT27

    Test Week 5 – Quiz

    Started 10/1/18 12:32 AM

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    Due Date 10/1/18 1:59 AM

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    Question 1

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    A patient who is experiencing acute alcohol withdrawal is being treated with intravenous

    lorazepam (Ativan). This drug achieves a therapeutic eect by

    Like all benzodiazepines, lorazepam increases the eects of GABA, which has

    an inhibitory eect on the CNS. However, none of the benzodiazepines act

    like GABA or increase the amount of GABA present. MAOIs inhibit

    monoamine oxidase and tricyclic antidepressants primarily aect serotonin

    and norepinephrine levels. SSRIs increase the availability of serotonin in the

    synapses.

    Question 2

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    Response

    Feedback:

    A 30-year-old woman is taking phenelzine (Nardil) 30mg PO tid. The nurse knows that at that

    dosage, the patient will need to be carefully monitored for

    The nurse will closely monitor for the adverse eects of phenelzine related

    to the anticholinergic eect of the drug, such as dizziness that tends to be

    more pronounced at dosages above 45 mg/day. Dizziness is also a sign of a

    phenelzine drug overdose. Constipation and dry mouth are also adverse

    eects, not diarrhea and increased secretions. Facial ushing is not an

    identied adverse eect of phenelzine.

    Question 3

    Response

    Feedback:

    A middle-aged patient was diagnosed with major depression after a suicide attempt several

    months ago and has failed to respond appreciably to treatment with SSRIs. As a result, his

    psychiatrist has prescribed phenelzine. When planning this patient’s subsequent care, what

    nursing diagnosis should the nurse prioritize?

    MAOIs such as phenelzine carry a signicant risk of injury that results from

    the multiple interactions associated with these drugs. Infection, impaired

    tissue perfusion, and constipation are less common, and less serious,

    adverse eects.

    Question 4

    Response

    Feedback:

    A nurse is assigned to a patient who is taking lithium. Which of the following drug serum

    levels would indicate that the patient is at risk for adverse eects of the drug?

    The therapeutic range for lithium is 0.6 to 1.2 mEq/L. A level of 0.3 mEq/L

    would not be in the therapeutic range and would therefore not produce a

    therapeutic response. Levels of 0.6 and 1.2 mEq/L would be within the

    therapeutic range and would not be expected to produce adverse eects. A

    level of 1.7 mEq/L would be a high level and place the patient at risk for

    adverse eects or overdose.

    Question 5

    Response

    Feedback:

    A trauma patient has been receiving frequent doses of morphine in the 6 days since his

    accident. This pattern of analgesic administration should prompt the nurse to carefully

    monitor the patient’s

    Morphine, like most opioid analgesics, creates a risk for constipation. The

    drug is unlikely to inuence the patient’s temperature, skin integrity, or urine

    specic gravity.

    Question 6

    Response

    Feedback:

    A patient has been admitted to the ICU because of multiple traumas due to a motor vehicle

    accident. The physician has ordered propofol (Diprivan) to be used for maintenance of

    sedation. Before administration of propofol, a priority assessment by the nurse would be to

    check for a history of

    Propofol is relatively contraindicated in patients with a history of seizure

    disorders because they are at risk of developing convulsions during the

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    recovery phase. This drug should be used with caution in patients with low

    blood pressure because it can aggravate this condition. Also, it should be

    used with caution in patients with increased intraocular pressure because it

    can cause a substantial reduction in cerebral perfusion. Because disorders of

    lipid metabolism can be aggravated by the emulsion vehicle in which

    propofol is delivered, it should be used with caution in patients with diabetic

    hyperlipidemia.

    Question 7

    Response

    Feedback:

    A patient has been hospitalized for treatment of substance abuse after being arrested and

    jailed for the past 24 hours. The patient is experiencing severe muscle and abdominal

    cramps, seizures, and acute psychosis due to abrupt withdrawal. Which of the following drug

    classes is the most likely cause of these severe and potentially fatal withdrawal symptoms?

    Abrupt withdrawal from long-term use of sedative–hypnotic drugs should

    never be attempted because withdrawal symptoms are serious and

    potentially fatal. Withdrawal symptoms include agitation, dysphoria,

    insomnia, vomiting, diarrhea, ataxia, hallucinations, acute psychosis, muscle

    and abdominal cramps, anorexia, and seizures. These symptoms may occur

    12 to 72 hours after the last use of the drug and may last up to 14 days. The

    abrupt withdrawal of benzodiazepines, opioids, and amphetamines does not

    cause such severe and potentially fatal withdrawal symptoms.

    Question 8

    Response

    Feedback:

    A nurse who works at an outpatient mental health clinic follows numerous clients who have

    schizophrenia, many of whom are being treated with olanzapine (Zyprexa). Which of the

    following clients likely has the highest susceptibility to the adverse eects of olanzapine?

    The use of olanzapine creates a signicant risk of hyperglycemia. This is of

    particular concern in patients and clients who have diabetes mellitus.

    Smoking aects the pharmacodynamics of olanzapine, but this is less likely

    to result in serious adverse eects. Obesity, low BMI, and recent antibiotic

    use are not associated with a signicantly increased risk of adverse eects.

    Question 9

    Response

    Feedback:

    A nurse is providing care for a patient who suered extensive burns to his extremities

    during a recent industrial accident. Topical lidocaine gel has been ordered to be applied to

    the surfaces of all his burns in order to achieve adequate pain control. When considering

    this order, the nurse should be aware that

    Applying lidocaine preparations to severely traumatized mucosa (large skin

    abrasions, eczema, and burns) can increase its absorption, which in turn

    increases the risk of systemic toxicity. Intravenous lidocaine is not normally

    used for analgesia. The destruction of nerve endings in a burn site does not

    mitigate the need for topical pain control and lidocaine does not need to be

    potentiated with another anesthetic.

    Question 10

    A 26-year-old professional began using cocaine recreationally several months ago and has

    begun using the drug on a daily basis over the past few weeks. He has noticed that he now

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    Response

    Feedback:

    g g g y p

    needs to take larger doses of cocaine in order to enjoy the same high that he used to

    experience when he rst used the drug. A nurse should recognize that this pattern

    exemplies

    With drug use over time, tolerance develops. Tolerance occurs when the

    body develops a natural resistance to the drug’s physical or euphoric eects,

    making it necessary to take increasing doses more frequently to achieve the

    desired eect.

    Question 11

    Response

    Feedback:

    A patient with mild low back pain has been advised to take acetaminophen. The nurse will

    inform him that excessive intake of acetaminophen may result in

    A patient taking acetaminophen should be taught the common adverse

    eects of the drug, which include rash, urticaria, and nausea. Nausea, not

    gastrointestinal distress, is a common adverse eect of acetaminophen.

    Flushing, dizziness, and feelings of tingling, heat, and fatigue are the most

    common adverse eects of sumatriptan, not acetaminophen.

    Question 12

    Response

    Feedback:

    Which of the following would be an expected outcome in a patient who has been given

    atropine during a medical emergency?

    Atropine is used to help restore normal sinus rhythm in emergency

    situations, such as symptomatic bradycardia, pulseless electrical activity,

    ventricular asystole, or cardiopulmonary resuscitation. It does not resolve

    acid-based imbalances or decreased level of consciousness and atropine

    increases, rather than decreases, blood pressure.

    Question 13

    Response

    Feedback:

    A 62-year-old woman has been prescribed a fentanyl transdermal patch for chronic cancer

    pain. The patient asks the nurse how long it will take for her to experience pain relief. The

    nurse will instruct the patient that she should feel pain relief in approximately

    The nurse will instruct the patient that it will take approximately 24 hours for

    the full pain-relieving eect of a fentanyl transdermal patch to occur.

    Question 14

    Response

    Feedback:

    A nurse is caring for a patient who has been admitted with acute cocaine intoxication. Which

    of the following vital signs would the nurse expect to nd initially when assessing the

    patient?

    CNS stimulants like cocaine initially increase heart rate and blood pressure.

    Cocaine impairs the uptake of norepinephrine and epinephrine by

    presynaptic nerve endings, thus activating the adrenergic systems and

    causing hypertension, tachycardia, and vasoconstriction.

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    Question 15

    Response

    Feedback:

    Morphine has been prescribed for a 28-year-old man with severe pain due to a back injury.

    The nurse will advise the patient to avoid

    The nurse should advise the patient to avoid alcohol and any other CNS

    depressants while taking morphine. These combinations can cause serious

    respiratory depression and sedation. Vitamin C, fatty foods, and dairy

    products are not known to interact with morphine.

    Question 16

    Response

    Feedback:

    The wife of a patient who is taking haloperidol calls the clinic and reports that her husband

    has taken the rst dose of the drug and it is not having a therapeutic eect. An appropriate

    response by the nurse would be

    The nurse should instruct the wife to continue oering her husband the drug

    and that it will probably take several days to reach its full therapeutic eect.

    The dosage would not be increased, decreased, or discontinued.

    Question 17

    Response

    Feedback:

    A nurse who provides care on an acute medicine unit has frequently recommended the use

    of nicotine replacement gum for patients who express a willingness to quit smoking during

    their admission or following their discharge. For which of the following patients would

    nicotine gum be contraindicated?

    Nicotine in any dosage form should not be used in patients immediately

    after myocardial infarction, or in those with life-threatening arrhythmias or

    severe or worsening angina pectoris. Antibiotics, anticoagulants, and renal

    failure are not contraindications for the use of nicotine as an aid to smoking

    cessation.

    Question 18

    Response

    Feedback:

    A nurse is caring for a patient who is in severe pain and is receiving an opioid analgesic.

    Which of the following would be the nurse’s priority assessments?

    The nurse must assess the patient’s pain intensity before and after

    administering an opioid analgesic. The respiratory rate and level of

    consciousness need to be assessed because respiratory depression and

    sedation are two adverse eects of opioid analgesics. Seizure activity,

    electrolytes, liver function, blood glucose level, and mental status may need

    to be assessed during opioid analgesic therapy related to adverse eects,

    but they would not be the priority assessments.

    Question 19

    Response

    Feedback:

    A patient has a history of tonic-clonic seizures that have been successfully treated with

    phenytoin (Dilantin) for several years. Phenytoin achieves a therapeutic eect by

    Phenytoin reversibly binds to sodium channels while they are in the inactive

    state. This binding delays the return of the channel to an active state.

    Because sodium can enter the cell to initiate an action potential only when

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    p y

    the channels are active, the time between action potentials is greatly

    lengthened, the neurons cannot re at an excessive rate, and excessive

    muscle contractions that occur in grand mal-type seizures are prevented.

    Phenytoin does not directly aect the function of calcium channels or levels

    of GABA and glutamate.

    Question 20

    Response

    Feedback:

    A patient who has been taking buspirone (BuSpar) for 1 week calls the clinic and reports to

    the nurse that the drug is not working. The patient informs the nurse that she is still having

    symptoms of anxiety. The nurse will tell the patient that

    The nurse will inform the patient that it will likely take 3 to 4 weeks of

    treatment before she notices consistent relief of her anxiety. However, some

    improvement is often seen within 7 to 10 days of starting therapy. Since the

    patient had only been taking the drug 1 week, there is no need to inform the

    physician. The nurse would not make the assumption that the medication is

    not going to work for the patient nor would she tell her that it would take up

    to 6 months to see therapeutic results.

    Question 21

    Response

    Feedback:

    A nurse is caring for a patient who abuses marijuana. The treatment for marijuana abuse

    consists mainly of

    Treatment for marijuana abuse consists mainly of nonpharmacologic

    interventions combined with an exercise program to help deal with

    withdrawal symptoms and cravings for the drug. Treatment of LSD and PCP

    use is necessary only when the user experiences a “bad trip.” Parlodel is

    given for cocaine addiction. Patients with acute inhalant intoxication may

    need respirator assistance.

    Question 22

    Response

    Feedback:

    Which of the following drugs used to treat anxiety would be appropriate for a patient who is

    a school teacher and is concerned about feeling sedated at work?

    Buspirone does not cause as much sedation and functional impairment as

    lorazepam, alprazolam, and diazepam. However, it can cause dizziness,

    nausea, headache, nervousness, lightheadedness, or excitement.

    Question 23

    Response

    Feedback:

    A patient is suering from acute inhalant intoxication. The priority nursing intervention will

    be to

    Patients suering from acute inhalant intoxication may experience hypoxia

    from CNS depression; therefore, the patient will most likely be receiving

    oxygen therapy. Epinephrine is contraindicated because of possible cardiac

    stimulation. Arrhythmias may occur. Monitoring blood pressure and pulse is

    important; however, the patient could be short of breath due to the hypoxia.

    Therefore, monitoring respirations would be the priority. Nausea and

    vomiting could be present, and the nurse would need to provide the patient

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    with an emesis basin, but it would not be the most important nursing

    intervention.

    Question 24

    Response

    Feedback:

    A 4-year-old child is brought to the emergency department by her mother. The mother

    reports that the child has been vomiting, and the nurse notes that the child’s face is ushed

    and she is diaphoretic. The mother thinks that the child may have swallowed carbachol

    drops. A diagnosis of cholinergic poisoning is made. Which of the following drugs would be

    administered?

    Acetylcholine and cevimeline are both cholinergic agonists, and, like

    carbachol, would be contraindicated in this patient. Administration of either

    of these drugs could be fatal. Nicotine is a direct-acting nicotinic agonist and

    is not indicated in cholinergic poisoning. Atropine is considered the antidote

    for cholinergic poisoning. The actions of atropine are a reduction in salivary,

    bronchial, and sweat gland secretions; mydriasis; cycloplegia; changes in

    heart rate; contraction of the bladder detrusor muscle and of the

    gastrointestinal smooth muscle; decreased gastric secretion; and decreased

    gastrointestinal motility.

    Question 25

    Response

    Feedback:

    A nurse will be prepared to administer naloxone (Narcan) to a patient who has had an

    overdose of morphine. Repeated doses of Narcan will be necessary because Narcan

    The duration of the morphine may be longer than the duration of naloxone.

    Therefore, naloxone has a shorter half-life than morphine. Repeated doses

    may be necessary to maintain reversal of the opiate’s eects. Naloxone does

    not increase the action of morphine, and it causes the respiratory rate to

    increase, not decrease. Dosage strength is not associated with drug

    duration.

    Question 26

    Response

    Feedback:

    A nurse is talking to an 18-year-old patient who has had a seizure disorder since she was 10

    years old and is taking phenytoin (Dilantin). The nurse should suggest that she take which of

    the following?

    Long-term phenytoin therapy is associated with folate deciency. Folic acid

    and phenytoin are structurally similar and thought to compete with each

    other for the same receptors. A deciency in folic acid in a pregnant woman

    can cause birth defects. Potassium, iron, and vitamin C do not compete with

    phenytoin nor are they directly aected by phenytoin.

    Question 27

    Response

    Feedback:

    A male patient has been brought to the emergency department during an episode of status

    epilepticus. Diazepam is to be administered intravenously. The nurse will be sure to

    When diazepam is administered intravenously during status epilepticus, the

    small veins in the dorsum of the hand or the wrist should be avoided. It

    should be injected slowly, no faster than 5 mg in 1 minute. Diazepam should

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    Monday, October 1, 2018 1:10:04 AM EDT

    not be mixed or diluted with other solutions or drugs, either in the syringe or

    in intravenous solutions.

    Question 28

    Response

    Feedback:

    A postsurgical patient has been provided with a morphine patient-controlled analgesic (PCA)

    but has expressed her reluctance to use it for fear of becoming addicted. How can the nurse

    best respond to this patient’s concerns?

    Addiction to opioids is a rare occurrence among hospital patients who do

    not have a history of drug abuse. It would be inappropriate to downplay the

    patient’s concerns, however. A more appropriate response would be to

    explain the phenomenon of dependence and to dierentiate it from

    addiction.

    Question 29

    Response

    Feedback:

    An elderly woman is slated for a hemiarthroplasty (hip replacement surgery) after falling and

    breaking her hip on the stairs outside her home. The woman’s pain in the time since her

    injury has been severe, and her care team has been treating it with morphine. Which of the

    following administration schedules is most likely to control the patient’s pain?

    The use of long-acting analgesia combined with short-acting opioids for

    breakthrough pain is a proactive pain management technique that

    maximizes therapeutic benet while minimizing the risks of adverse eects.

    Question 30

    Response

    Feedback:

    A 64-year-old-patient has been prescribed lorazepam (Ativan) because of increasing periods

    of anxiety. The nurse should be careful to assess for

    The patient who has history of alcohol or substance abuse may be a poor

    candidate for lorazepam because the patient is more likely to develop

    dependence on the drug. Alcohol will also have an additive eect with

    lorazepam. A diet high in fat and carbohydrates or nicotine use should not

    aect the use of lorazepam.

    Question 31

    When completing this quiz, did you comply with Walden University’s Code of

    Conduct including the expectations for academic integrity?

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    NURS-6521 Advanced Pharmacology – Week 5 – Quiz

  • NURS 6521 Advanced Pharmacology – Week 5 – Quiz

    NURS 6521 Advanced Pharmacology – Week 5 – Quiz

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    30 out of 30 points

    Time Elapsed

    46 minutes out of 1 hour and 15 minutes

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    Please answer each question below and click 
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     when you have completed the Quiz.

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     Question 1

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    1 out of 1 points

     

    A middle-aged patient was diagnosed with major depression after a suicide attempt several months ago and has failed to respond appreciably to treatment with SSRIs. As a result, his psychiatrist has prescribed phenelzine. When planning this patient’s subsequent care, what nursing diagnosis should the nurse prioritize?

    Response Feedback:

    MAOIs such as phenelzine carry a significant risk of injury that results from the multiple interactions associated with these drugs. Infection, impaired tissue perfusion, and constipation are less common, and less serious, adverse effects. NURS 6521 Advanced Pharmacology – Week 5 – Quiz

     Question 2

    1 out of 1 points

     

    A male patient has been brought to the emergency department during an episode of status epilepticus. Diazepam is to be administered intravenously. The nurse will be sure to

    Response Feedback:

    When diazepam is administered intravenously during status epilepticus, the small veins in the dorsum of the hand or the wrist should be avoided. It should be injected slowly, no faster than 5 mg in 1 minute. Diazepam should not be mixed or diluted with other solutions or drugs, either in the syringe or in intravenous solutions.

     Question 3

    1 out of 1 points

     

    A nurse who works at an outpatient mental health clinic follows numerous clients who have schizophrenia, many of whom are being treated with olanzapine (Zyprexa). Which of the following clients likely has the highest susceptibility to the adverse effects of olanzapine?

    Response Feedback:

    The use of olanzapine creates a significant risk of hyperglycemia. This is of particular concern in patients and clients who have diabetes mellitus. Smoking affects the pharmacodynamics of olanzapine, but this is less likely to result in serious adverse effects. Obesity, low BMI, and recent antibiotic use are not associated with a significantly increased risk of adverse effects. NURS 6521 Advanced Pharmacology – Week 5 – Quiz

     Question 4

    1 out of 1 points

     

    A 4-year-old child is brought to the emergency department by her mother. The mother reports that the child has been vomiting, and the nurse notes that the child’s face is flushed and she is diaphoretic. The mother thinks that the child may have swallowed carbachol drops. A diagnosis of cholinergic poisoning is made. Which of the following drugs would be administered?

    Response Feedback:

    Acetylcholine and cevimeline are both cholinergic agonists, and, like carbachol, would be contraindicated in this patient. Administration of either of these drugs could be fatal. Nicotine is a direct-acting nicotinic agonist and is not indicated in cholinergic poisoning. Atropine is considered the antidote for cholinergic poisoning. The actions of atropine are a reduction in salivary, bronchial, and sweat gland secretions; mydriasis; cycloplegia; changes in heart rate; contraction of the bladder detrusor muscle and of the gastrointestinal smooth muscle; decreased gastric secretion; and decreased gastrointestinal motility.

     Question 5

    1 out of 1 points

     

    A trauma patient has been receiving frequent doses of morphine in the 6 days since his accident. This pattern of analgesic administration should prompt the nurse to carefully monitor the patient’s

    Response Feedback:

    Morphine, like most opioid analgesics, creates a risk for constipation. The drug is unlikely to influence the patient’s temperature, skin integrity, or urine specific gravity. NURS 6521 Advanced Pharmacology – Week 5 – Quiz

     Question 6

    1 out of 1 points

     

    A patient has been prescribed zolpidem (Ambien) for short-term treatment of insomnia. Which of the following will the nurse include in a teaching plan for this patient? (Select all that apply.)

    Response Feedback:

    Zolpidem generally is not used for more than 7 to 10 days at a time. It induces sleep rapidly and should be taken immediately before going to bed. It is true that the drug does not seem to produce residual effects the next morning or cause prolonged rebound effects when it is discontinued. It is available in both quick-onset and continuous-release oral forms, and common adverse effects of the drug are headache, prolonged drowsiness, and dizziness.

     Question 7

    1 out of 1 points

     

    NURS 6521 Advanced Pharmacology – Week 5 – Quiz

    A nurse is caring for a patient who is in severe pain and is receiving an opioid analgesic. Which of the following would be the nurse’s priority assessments?

    Response Feedback:

    The nurse must assess the patient’s pain intensity before and after administering an opioid analgesic. The respiratory rate and level of consciousness need to be assessed because respiratory depression and sedation are two adverse effects of opioid analgesics. Seizure activity, electrolytes, liver function, blood glucose level, and mental status may need to be assessed during opioid analgesic therapy related to adverse effects, but they would not be the priority assessments.

     Question 8

    1 out of 1 points

     

    A nurse is caring for a patient who has been admitted with acute cocaine intoxication. Which of the following vital signs would the nurse expect to find initially when assessing the patient?

    Response Feedback:

    CNS stimulants like cocaine initially increase heart rate and blood pressure. Cocaine impairs the uptake of norepinephrine and epinephrine by presynaptic nerve endings, thus activating the adrenergic systems and causing hypertension, tachycardia, and vasoconstriction.

     Question 9

    1 out of 1 points

     

    A 39-year-old patient who is having trouble sleeping is beginning drug treatment with zaleplon (Sonata). The nurse will be sure to ask the patient if she is taking

    Response Feedback:

    The nurse will assess for cimetidine use. Cimetidine greatly increases the level of circulating zaleplon and could cause toxic effects in the patient. Secobarbital is a barbiturate, and oxycodone and meperidine are narcotics that would not be used with lorazepam because the combinations may depress respiratory drive, create severe hypotension or bradycardia, and substantially alter level of consciousness. NURS 6521 Advanced Pharmacology – Week 5 – Quiz

     Question 10

    1 out of 1 points

     

    A patient has been admitted to the ICU because of multiple traumas due to a motor vehicle accident. The physician has ordered propofol (Diprivan) to be used for maintenance of sedation. Before administration of propofol, a priority assessment by the nurse would be to check for a history of

    Response Feedback:

    Propofol is relatively contraindicated in patients with a history of seizure disorders because they are at risk of developing convulsions during the recovery phase. This drug should be used with caution in patients with low blood pressure because it can aggravate this condition. Also, it should be used with caution in patients with increased intraocular pressure because it can cause a substantial reduction in cerebral perfusion. Because disorders of lipid metabolism can be aggravated by the emulsion vehicle in which propofol is delivered, it should be used with caution in patients with diabetic hyperlipidemia.

     Question 11

    1 out of 1 points

     

    A nurse who provides care on an acute medicine unit has frequently recommended the use of nicotine replacement gum for patients who express a willingness to quit smoking during their admission or following their discharge. For which of the following patients would nicotine gum be contraindicated?

    Response Feedback:

    Nicotine in any dosage form should not be used in patients immediately after myocardial infarction, or in those with life-threatening arrhythmias or severe or worsening angina pectoris. Antibiotics, anticoagulants, and renal failure are not contraindications for the use of nicotine as an aid to smoking cessation.

     Question 12

    1 out of 1 points

     

    A patient who is experiencing acute alcohol withdrawal is being treated with intravenous lorazepam (Ativan). This drug achieves a therapeutic effect by

    Response Feedback:

    Like all benzodiazepines, lorazepam increases the effects of GABA, which has an inhibitory effect on the CNS. However, none of the benzodiazepines act like GABA or increase the amount of GABA present. MAOIs inhibit monoamine oxidase and tricyclic antidepressants primarily affect serotonin and norepinephrine levels. SSRIs increase the availability of serotonin in the synapses. NURS 6521 Advanced Pharmacology – Week 5 – Quiz

     Question 13

    1 out of 1 points

     

    An elderly woman is slated for a hemiarthroplasty (hip replacement surgery) after falling and breaking her hip on the stairs outside her home. The woman’s pain in the time since her injury has been severe, and her care team has been treating it with morphine. Which of the following administration schedules is most likely to control the patient’s pain?

    Response Feedback:

    The use of long-acting analgesia combined with short-acting opioids for breakthrough pain is a proactive pain management technique that maximizes therapeutic benefit while minimizing the risks of adverse effects.

     Question 14

    1 out of 1 points

     

    A nurse will be prepared to administer naloxone (Narcan) to a patient who has had an overdose of morphine. Repeated doses of Narcan will be necessary because Narcan

    Response Feedback:

    The duration of the morphine may be longer than the duration of naloxone. Therefore, naloxone has a shorter half-life than morphine. Repeated doses may be necessary to maintain reversal of the opiate’s effects. Naloxone does not increase the action of morphine, and it causes the respiratory rate to increase, not decrease. Dosage strength is not associated with drug duration.

     Question 15

    1 out of 1 points

     

    A nurse is talking to an 18-year-old patient who has had a seizure disorder since she was 10 years old and is taking phenytoin (Dilantin). The nurse should suggest that she take which of the following?

    Response Feedback:

    Long-term phenytoin therapy is associated with folate deficiency. Folic acid and phenytoin are structurally similar and thought to compete with each other for the same receptors. A deficiency in folic acid in a pregnant woman can cause birth defects. Potassium, iron, and vitamin C do not compete with phenytoin nor are they directly affected by phenytoin.

     Question 16

    1 out of 1 points

     

    A nurse works in a sleep disorder clinic and is responsible for administering medications to the patients. Which of the following patients would be most likely to receive zaleplon (Sonata)?

    Response Feedback:

    The nurse will most likely administer the zaleplon to the 35-year-old man who is having difficulty falling asleep, but once asleep can stay asleep. Zolpidem would most likely be administered to the 20-year-old who will take a sleep aid only once a week. Eszopiclone (Lunesta) will be given to the 52-year-old woman who needs to fall asleep quickly and has trouble staying asleep. The 46-year-old man will likely receive trazodone (Desyrel). This drug is given as a sleep aid for a patient who is taking an antidepressant.

     Question 17

    1 out of 1 points

     

    A 64-year-old-patient has been prescribed lorazepam (Ativan) because of increasing periods of anxiety. The nurse should be careful to assess for

    Response Feedback:

    The patient who has history of alcohol or substance abuse may be a poor candidate for lorazepam because the patient is more likely to develop dependence on the drug. Alcohol will also have an additive effect with lorazepam. A diet high in fat and carbohydrates or nicotine use should not affect the use of lorazepam.

     Question 18

    1 out of 1 points

     

    A patient who has been taking buspirone (BuSpar) for 1 week calls the clinic and reports to the nurse that the drug is not working. The patient informs the nurse that she is still having symptoms of anxiety. The nurse will tell the patient that

    Response Feedback:

    The nurse will inform the patient that it will likely take 3 to 4 weeks of treatment before she notices consistent relief of her anxiety. However, some improvement is often seen within 7 to 10 days of starting therapy. Since the patient had only been taking the drug 1 week, there is no need to inform the physician. The nurse would not make the assumption that the medication is not going to work for the patient nor would she tell her that it would take up to 6 months to see therapeutic results.

     Question 19

    1 out of 1 points

     

    A patient has been hospitalized for treatment of substance abuse after being arrested and jailed for the past 24 hours. The patient is experiencing severe muscle and abdominal cramps, seizures, and acute psychosis due to abrupt withdrawal. Which of the following drug classes is the most likely cause of these severe and potentially fatal withdrawal symptoms?

    Response Feedback:

    Abrupt withdrawal from long-term use of sedative–hypnotic drugs should never be attempted because withdrawal symptoms are serious and potentially fatal. Withdrawal symptoms include agitation, dysphoria, insomnia, vomiting, diarrhea, ataxia, hallucinations, acute psychosis, muscle and abdominal cramps, anorexia, and seizures. These symptoms may occur 12 to 72 hours after the last use of the drug and may last up to 14 days. The abrupt withdrawal of benzodiazepines, opioids, and amphetamines does not cause such severe and potentially fatal withdrawal symptoms. NURS 6521 Advanced Pharmacology – Week 5 – Quiz

     Question 20

    1 out of 1 points

     

    A nurse is assigned to a patient who is taking lithium. Which of the following drug serum levels would indicate that the patient is at risk for adverse effects of the drug?

    Response Feedback:

    The therapeutic range for lithium is 0.6 to 1.2 mEq/L. A level of 0.3 mEq/L would not be in the therapeutic range and would therefore not produce a therapeutic response. Levels of 0.6 and 1.2 mEq/L would be within the therapeutic range and would not be expected to produce adverse effects. A level of 1.7 mEq/L would be a high level and place the patient at risk for adverse effects or overdose.

     Question 21

    1 out of 1 points

     

    Which of the following would be an expected outcome in a patient who has been given atropine during a medical emergency?

    Response Feedback:

    Atropine is used to help restore normal sinus rhythm in emergency situations, such as symptomatic bradycardia, pulseless electrical activity, ventricular asystole, or cardiopulmonary resuscitation. It does not resolve acid-based imbalances or decreased level of consciousness and atropine increases, rather than decreases, blood pressure.

     Question 22

    1 out of 1 points

     

    A patient who is experiencing withdrawal from heavy alcohol use have developed psychosis and been treated with haloperidol. Which of the following assessment findings should prompt the care team to assess the patient for neuroleptic malignant syndrome?

    Response Feedback:

    Neuroleptic malignant syndrome is characterized by fever, sweating, tachycardia, muscle rigidity, tremor, incontinence, stupor, leukocytosis, elevated creatinine phosphokinase levels, and renal failure. Agitation, pruritis, thirst, and increased urine output are not indicative of neuroleptic malignant syndrome.

     Question 23

    1 out of 1 points

     

    A 20-year-old man has begun treatment of the psychotic symptoms of schizophrenia using olanzapine (Zyprexa). Which of the following symptoms would be categorized as a negative symptom of schizophrenia?

    Response Feedback:

    The negative symptoms of schizophrenia include flat or blunted emotions, lack of pleasure or interest in things (anhedonia), and limited speech. The positive symptoms of schizophrenia, and the most recognizable symptoms, include delusions (e.g., paranoia or distorted perceptions of other people’s intentions) and hallucinations.

     Question 24

    1 out of 1 points

     

    The wife of a patient who is taking haloperidol calls the clinic and reports that her husband has taken the first dose of the drug and it is not having a therapeutic effect. An appropriate response by the nurse would be

    Response Feedback:

    The nurse should instruct the wife to continue offering her husband the drug and that it will probably take several days to reach its full therapeutic effect. The dosage would not be increased, decreased, or discontinued.

     Question 25

    1 out of 1 points

     

    A 62-year-old woman has been prescribed a fentanyl transdermal patch for chronic cancer pain. The patient asks the nurse how long it will take for her to experience pain relief. The nurse will instruct the patient that she should feel pain relief in approximately

    Response Feedback:

    The nurse will instruct the patient that it will take approximately 24 hours for the full pain-relieving effect of a fentanyl transdermal patch to occur. NURS 6521 Advanced Pharmacology – Week 5 – Quiz

     Question 26

    1 out of 1 points

     

    A patient has been prescribed lithium therapy. Which of the following signs and symptoms will the nurse tell the patient to report immediately?

    Response Feedback:

    Muscle twitching is an early symptom of lithium toxicity and should be reported immediately. Muscle twitching indicates that a dosage change may be needed. Increased thirst and urination are acute effects of lithium, whereas hair loss is a chronic adverse effect.

     Question 27

    1 out of 1 points

     

    A patient with mild low back pain has been advised to take acetaminophen. The nurse will inform him that excessive intake of acetaminophen may result in

    Response Feedback:

    A patient taking acetaminophen should be taught the common adverse effects of the drug, which include rash, urticaria, and nausea. Nausea, not gastrointestinal distress, is a common adverse effect of acetaminophen. Flushing, dizziness, and feelings of tingling, heat, and fatigue are the most common adverse effects of sumatriptan, not acetaminophen.

     Question 28

    1 out of 1 points

     

    A postsurgical patient has been provided with a morphine patient-controlled analgesic (PCA) but has expressed her reluctance to use it for fear of becoming addicted. How can the nurse best respond to this patient’s concerns?

    Response Feedback:

    Addiction to opioids is a rare occurrence among hospital patients who do not have a history of drug abuse. It would be inappropriate to downplay the patient’s concerns, however. A more appropriate response would be to explain the phenomenon of dependence and to differentiate it from addiction. NURS 6521 Advanced Pharmacology – Week 5 – Quiz

     Question 29

    1 out of 1 points

     

    Which of the following drugs used to treat anxiety would be appropriate for a patient who is a school teacher and is concerned about feeling sedated at work?

    Response Feedback:

    Buspirone does not cause as much sedation and functional impairment as lorazepam, alprazolam, and diazepam. However, it can cause dizziness, nausea, headache, nervousness, lightheadedness, or excitement.

     Question 30

    1 out of 1 points

     

    A 30-year-old woman is taking phenelzine (Nardil) 30mg PO tid. The nurse knows that at that dosage, the patient will need to be carefully monitored for

    Response Feedback:

    The nurse will closely monitor for the adverse effects of phenelzine related to the anticholinergic effect of the drug, such as dizziness that tends to be more pronounced at dosages above 45 mg/day. Dizziness is also a sign of a phenelzine drug overdose. Constipation and dry mouth are also adverse effects, not diarrhea and increased secretions. Facial flushing is not an identified adverse effect of phenelzine.

     Question 31

    0 out of 0 points

     

    When completing this quiz, did you comply with Walden University’s Code of Conduct including the expectations for academic integrity? NURS 6521 Advanced Pharmacology – Week 5 – Quiz

  • NURS 6521 Week 1 Discussion – Pharmacokinetics and pharmacodynamics Sample Essays

    NURS 6521 Week 1 Discussion – Pharmacokinetics and pharmacodynamics Sample Essays

    Week 1 Discussion

    Pharmacokinetics and pharmacodynamics are important factors in the plan of care for any patient population. When taking care of elderly patients and prescribing medications, it is important for healthcare prescribers to know how medications will affect elderly patients. One example of the importance of pharmacokinetics and pharmacodynamics playing a factor in patient care was during the treatment of a 75-year-old white female. She was forgetful and lived alone will little outside help for daily task and healthcare. This patient used acetaminophen (Tylenol) for pain on a regular basis to treat her arthritis and generalized pain. During a detailed history, she reported that she was careful not to exceed the recommended daily dose of acetaminophen. Additional medications taken by this patient included digoxin for an apparent cardiac condition. The patient presented with nausea, vomiting and abdominal pain that was sudden in onset.  Acetaminophen, a safe and effective pain reliever, is one of the most popular OTC pain relivers in the U.S.  Elevated LFTs and renal function labs provided clues to the healthcare provider that drug toxicity may be present. NURS 6521 Week 1 Discussion – Pharmacokinetics and pharmacodynamics Sample Essays.

    BUY A PLAGIARISM-FREE PAPER HERE

    Pharmacokinetics is defined as the study of the time course of drug absorption, distribution, metabolism, and excretion (Spruill et al., 2014). Clinical pharmacokinetics is the application of pharmacokinetic principles to the safe and effective therapeutic management of drugs in an individual patient (Spruill et al., 2014). Pharmacodynamics refers to the relationship between drug concentration at the site of action and the resulting effect, including the time course and intensity of therapeutic and adverse effects (Pea, 2012). The effect of a drug present at the site of action is determined by that drug’s binding with a receptor.

    Normal aging of organs and systems leads to diminished function in many areas including decreased neuromuscular strength and reaction time to losses in memory and cognition (Jankovic, Illic, Bukumiric & Jankovic, n.d.).  There is a decreasing trend in hepatic metabolizing capacity with advancing years that can affect the ability to clear therapeutic drugs and environmental chemicals. This factor, combined with decreased renal clearance, causes prolonged retention of numerous drugs in elderly individuals.  The elderly consume a disproportionate quantity of drugs, with those older than 65 taking, on average, two to six prescribed and one to three nonprescription drugs at any one time (Cecilia et al., 2018). About 70 to 80% of an oral dose of digoxin is absorbed, mainly in the proximal part of the small intestine (Martin-Suarez et al., n.d.). The degree of binding to serum albumin is 20 to 30% (Martin-Suarez et al., n.d.). Digoxin is extensively distributed in the tissues, as reflected by the large volume of distribution. High concentrations are found in the heart and kidneys, but the skeletal muscles form the largest digoxin storage. NURS 6521 Week 1 Discussion – Pharmacokinetics and pharmacodynamics Sample Essays.

    Polypharmacy is the administration of numerous drugs, usually more than five medications, to a single patient (Jankovic, Illic, Bukumiric & Jankovic, n.d.). This practice is very common in elderly individuals and increases the risks for drug interaction and side effects. In addition, there are numerous pharmacodynamic factors in the CNS of elderly subjects that may affect sensitivity to neuroactive agents. Changes in central cholinergic pathways, including decreased number of brain acetylcholine postsynaptic receptors, have been demonstrated in rodent models of aging and may contribute to the progressive decline in memory and cognition in elderly individuals (Pea, 2012). Liver function is generally considered to be maintained well into old age. A variety of drugs can induce hepatotoxicity with the possibility that reduced cellular defenses and reserve capacity could make the elderly individuals’ liver more susceptible to medications. NURS 6521 Week 1 Discussion – Pharmacokinetics and pharmacodynamics Sample Essays.

    Elderly individuals are at greater risk of drug interactions due to metabolic changes and decreased drug clearance associated with aging. This risk becomes compounded with each additional number of drugs used. Several factors in older individuals contribute to their increased risk for developing a drug-related problem. They include frailty, coexisting medical problems, memory issues, and use of multiple prescribed and non-prescribed medications (Cecilia et al., 2018).  A balance is required between over- and under-prescribing. Multiple medications are often required to manage clinically complex older adults. Clinicians are often challenged with the need to match the complex needs of their older patients with those of disease-specific clinical practice guidelines.

    A stepwise approach to prescribing for older adults should include: periodic review of current drug therapy; discontinuing unnecessary medications; considering nonpharmacologic alternative strategies; considering safer alternative medications; using the lowest possible effective dose; including all necessary beneficial medications (Spruill et al., 2014). Primary goals of clinical pharmacokinetics include enhancing efficacy and decreasing toxicity of a patient’s drug therapy. The development of strong correlations between drug concentrations and their pharmacologic responses has enabled clinicians to apply pharmacokinetic principles to actual patient situations. A drug’s effect is often related to its concentration at the site of action, so it would be useful to monitor this concentration. NURS 6521 Week 1 Discussion – Pharmacokinetics and pharmacodynamics Sample Essays.

    Phillip Comalander

    References:

    Cecilia, L., Åsa, B., Nina, V., Anders, B., & Patrik, M. (2018). Effects of medication reviews on use of potentially inappropriate medications in elderly patients; a cross-sectional study in Swedish primary care. 
    BMC Health Services Research, Vol 18, Iss 1, Pp 1-9 (2018)
    , (1), 1. doi:10.1186/s12913-018-3425-y

    Jankovic, S., Illic, D., Bukumiric, Z., & Jankovic, S. (n.d). Impact of Educational Intervention on Prescribing Inappropriate Medication to Elderly Nursing Homes Residents. 
    Srpski Arhiv Za Celokupno Lekarstvo
    , 
    143
    (3-4), 174-179.

    Martin-Suarez, A., Calvo Hernandez, M. V., Garcia Gonzalez, D., Macias Nunez, J. F., & Ardanuy Albajar, R. (n.d). A New Method for Individualized Digoxin Dosing in Elderly Patients. 
    Drugs & Aging
    , 
    33
    (4), 277-284.

    Pea, F. (2012). 
    Pharmacokinetics in everyday clinical practice. [electronic resource]
    . Torino: SEEd, 2012.

    Spruill, W., Spruill, W. J., Wade, W. E., DiPiro, J. T., Coleman, R., Hershey, J., & Wade, D. (2014). 
    Concepts in clinical pharmacokinetics
    . Bethesda, Maryland: American Society of Health-System Pharmacists, 2014.

     

    Initial Post

    Pharmacokinetics and Pharmacodynamics

    Many different patient factors affect the pharmacokinetics and pharmacodynamics of medications. As providers, it is imperative to have a sound understanding of the pathophysiology of diseases and how they affect the body. According to Arcangelo and Petterson (2013), pharmacokinetics focuses on what the body does to the drug while pharmacodynamics concerns what the drug does to the body. NURS 6521 Week 1 Discussion – Pharmacokinetics and pharmacodynamics Sample Essays.

    Patient Scenario

    Ms. J. is a 28-year-old gravida five para four, 38 weeks gestation admitted to labor and delivery with the complaint of spontaneous rupture of membranes. Ms. J. has limited prenatal care with a history of drug use. Upon examination, she does have rupture of membranes, and she is five centimeters dilated. Ms. J. is given Stadol 2mg IVP for pain, and 30 minutes to an hour later, she is requesting more pain medication. Ms. J. states she needs something stronger because the Stadol is not working. The physician ordered Stadol 1mg IVP every hour as needed. Ms. J. was still complaining of pain with the medication change and becomes very agitated, cursing staff, and uncooperative. The doctor was notified again of patient complaint of pain and behavior. The doctor was hesitant on prescribing anything else for pain but eventually ordered Demerol 25mg IVP which the patient only required one dose before delivery.

    Factors Influencing the Pharmacokinetics and Pharmacodynamic Process

    The patient’s history of drug use significantly impacts the body’s utilization of medications, and the effect medication has on the body. Patients with a history of substance abuse make up 14% of the admissions to acute care units (da Cunha, 2015). According to Dunn and Neuman (2012), tolerance to pain medication develops from chronic use of a controlled substance which leads to the patient requiring increased amount of the same drug to achieve the desired effect. NURS 6521 Week 1 Discussion – Pharmacokinetics and pharmacodynamics Sample Essays.

    Personalized Plan of Care

    Individualized care for this patient was to control her pain while trying to avoid respiratory depression of the newborn after delivery. According to Dunn and Neuman (2012), providers must believe and accept a patient’s report of pain to successfully manage it. Undertreatment of a patient’s pain can cause pseudoaddiction in which the patient exhibit behaviors similar to addiction but is due to inadequate pain management (Dunn & Neuman, 2012). As a provider, it is important to have a pain management plan in place for patients with substance abuse and refer them to the appropriate agencies for treatment after delivery.

     

    References

    Arcangelo, V. P., & Peterson, A. M. (Eds.). (2013).
    Pharmacotherapeutics for advanced practice: A practical approach
    (3
    rd
    ed.). Ambler, PA: Lippincott Williams & Wilkins.

    Da Cunha, B. F. (2015). Ethics and undertreatment of pain in patients with a history of drug abuse.
    MEDSURG Nursing,
    4-16.

    Dunn, D., & Neuman, J. (2012). How substance abuse impacts pain management in acute care.
    Nursing, 42
    (8), 66-68. NURS 6521 Week 1 Discussion – Pharmacokinetics and pharmacodynamics Sample Essays.

    NURS 6521: Advanced Pharmacology

    Week One: Basic Pharmacotherapeutic Concepts

    Prescribing appropriate medications is an essential role of health care providers and practitioners in the treatment of medical conditions, preventing negative health status and promoting health. As advanced practice registered nurses (APRN), understanding the process of how drugs and human body interacts is critical in managing our patients properly. As stated by the National Council of State Boards of Nursing, APRNs are prepared by education and certification to assess, diagnose, and manage patient problems, order tests, and prescribe medications (n.d.). Competence in drug therapy is one of the fundamental functions of APRNs particularly, nurse practitioners. The purpose of this week’s discussion will analyze how patient factors influence the processes of pharmacokinetic and pharmacodynamics in individuals to develop an effective plan of care.

    Pharmacokinetics and Pharmacodynamics

    Pharmacokinetics refers to the movement of the drug through the body while pharmacodynamics indicates how the drug is affecting the body (Arcangelo, Peterson, Reinhold, & Wilbur, 2017, p. 17). Both processes involve the interaction of the medication and human body functions. Several factors such as age, gender, ethnicity, behavior, genetics, and pathophysiological conditions can influence the processes of pharmacokinetics and pharmacodynamics of an individual. An example is the physiologic changes that occur during the aging process which can lead to several alterations in the absorption, distribution, metabolism, including excretion of drugs and the modifications in pharmacokinetics often affect drug properties such as concentration or rate of clearance, deviations in pharmacodynamics resulting changes in drug’s magnitude of effects and subsequent likelihood of adverse consequences (Sera & Uritsky, 2016). Every individual can have different ways of processing drugs and unique means of getting the medication effects. Comprehensively understanding influences that can affect the drug-body interaction is crucial in achieving the desired outcome and preventing unwanted complications. NURS 6521 Week 1 Discussion – Pharmacokinetics and pharmacodynamics Sample Essays.

    The Case of Age and Pathophysiological Changes Effects on Drug Interactions

    Reduced muscle strength, increased inactivity, more severe chronic health conditions, and increased use of prescription medications are risk factors for falls among older Americans and fall injury rates are almost seven times higher for older adults with poor health than for those with excellent health (Centers for Disease Control and Prevention, 2016). Due to physiologic changes associated with aging, use of certain medications can increase the risks of fall incident among the elderly population. In the past years that I have worked as a registered nurse in long-term care facilities and acute hospitals, I have witnessed the prevalence of the negative consequences of fall incidents among the elderly population. Although age itself creates a risk for adverse drug reactions, polypharmacy and the multiplicity of drugs taken by older adults present the higher risk which can result in significant health outcomes, such as falls and fractures (Arcangelo, Peterson, Reinhold, & Wilbur, 2017, p. 77). Polypharmacy is defined as the use of multiple drugs by a patient, such as the use of more medications than indicated, the indication of inappropriate prescriptions, the use of two or more drugs to treat the same disease or same therapeutic class (Bellostas Muñoz, Caudevilla Martinez, Crespo Avellana, Diez-Manglano, Gomez Aguirre, & Velilla Marco, 2017). As older population may experience multiple complex conditions, they are at risks of taking various medications prescribed by different specialists, providers, and practitioners causing increased risks of adverse drug reactions from polypharmacy. Furthermore, many of the elderly population have been in various hospitals and transitional care facilities resulting to the accumulation of prescribed medications. As studied in an article, polypharmacy is independently associated with adverse outcomes in frailty particularly where there is a decline in nutritional status, functional ability, and cognitive capacity particularly, increasing the risk of falls in the elderly population (Heard, Jubraj, Marvin, Poots, Rajagopalan, & Ward, 2017). Due to the complexity of their medical condition and physiologic changes, multiple drug prescriptions can result in drug-body interaction causing adverse effects such as cognitive decline, behavioral changes, alterations in their activities of daily living and reduction in functional status. NURS 6521 Week 1 Discussion – Pharmacokinetics and pharmacodynamics Sample Essays.

    Personalized Plan of Care

    Proper prescribing consists of selecting drugs that have clear evidence for their indicated use, which is appropriate for the patient’s circumstances, are well tolerated and cost-effective and whose benefits outweigh the risks including periodic reviews of prescriptions, especially when the patient changes doctor and during health care transitions (Bellostas Muñoz, Caudevilla Martinez, Crespo Avellana, Diez-Manglano, Gomez Aguirre, & Velilla Marco, 2017). As advanced practice nurses, reviewing the medications prescribed to the patient before adding new prescriptions needs to be exercised to avoid unnecessary use of certain drugs. Also, educating patients and their caregivers to immediately report changes in signs and symptoms that can be related to drug interactions should be encouraged to evaluate the elderly’s medications timely before an adverse event can occur. NURS 6521 Week 1 Discussion – Pharmacokinetics and pharmacodynamics Sample Essays.

     

    Reference

    Arcangelo, V. P., Peterson, A. M., Reinhold, J. A., & Wilbur, V. (Eds.). (2017). Pharmacotherapeutics for advanced practice: A practical approach (4th ed.). Ambler, PA: Lippincott Williams & Wilkins.

    Bellostas Muñoz, L., Caudevilla Martinez, A., Crespo Avellana, M., Diez-Manglano, J., Gomez Aguirre, N., & Velilla Marco, J. (2017). Symposium. Polypathology: Polypathology, polypharmacy, medication regimen complexity and drug therapy appropriateness. Revista Clínica Española (English Edition), 217289-295. doi:10.1016/j.rceng.2016.12.008. Retrieved from https://www-sciencedirect-com.ezp.waldenulibrary.org/science/article/pii/S2254887417300115?

    Centers for Disease Control and Prevention. (2016, September). Falls are leading cause of injury and death in older Americans. Retrieved from https://www.cdc.gov/media/releases/2016/p0922-older-adult-falls.html

    Heard, K., Jubraj, B., Marvin, V., Poots, A. J., Rajagopalan, A., & Ward, E. (2017). Deprescribing medicines in the acute setting to reduce the risk of falls. European Journal of Hospital Pharmacy-Science and Practice, 24(1), 10-15. Retrieved from http://ejhp.bmj.com.ezp.waldenulibrary.org/content/24/1/10

    National Council of State Boards of Nursing. (n.d.). APRNs in the U.S. Retrieved from https://ncsbn.org/aprn.htm

    Sera, L., & Uritsky, T. (2016). Pharmacokinetic and pharmacodynamics changes in older adults and implications for palliative care. Progress in Palliative Care, 24(5), 255-261. doi:10.1080/09699260.2016.1192319. Retrieved from https://eds-a-ebscohost-com.ezp.waldenulibrary.org/eds/pdfviewer/pdfviewer?vid=6&sid=a5084331-cc2f-4444-b694-778f0a63d346%40sessionmgr4009 NURS 6521 Week 1 Discussion – Pharmacokinetics and pharmacodynamics Sample Essays

  • NURS 5052/NURS 6052: Essentials of Evidence-Based Practice

    NURS 5052/NURS 6052: Essentials of Evidence-Based Practice

     
    Course Project Overview

    Evidence-based practice involves a great deal more than simply reading nursing periodicals on a regular basis. Nurses can take a more proactive approach to evidence-based practice by identifying authentic problems and concerns, and then using that to guide their inquiries into current research. In this way, nurses can connect the results of relevant research studies to their nursing practice.

    BUY A PLAGIARISM-FREE PAPER HERE

    For the Course Project, you identify and apply relevant research to a specific nursing topic or problem. You begin by formulating an answerable question that is relevant to nursing and evidence-based practice. In later weeks of this course, you continue the course project by conducting a literature review and then determining how the evidence from the literature can be applied to nursing practice. NURS 5052/NURS 6052: Essentials of Evidence-Based Practice.

     

    Before you begin, review this document, which contains information about all three parts of the Course Project.

     

    Note:
    This Course Project will serve as the
    Portfolio Assignment
    for the course. In addition to submitting portions of this Project in Weeks 2 and 5, you will turn in all three deliverables in
    Week 10
    .

     

    Course Project: Part 1–Identifying a Researchable Problem

     

    One of the most challenging aspects of EBP is to actually identify the answerable question.

    —Karen Sue Davies

     

    Formulating a question that targets the goal of your research is a challenging but essential task. The question plays a crucial role in all other aspects of the research, including the determination of the research design and theoretical perspective to be applied, which data will be collected, and which tools will be used for analysis. NURS 5052/NURS 6052: Essentials of Evidence-Based Practice. It is therefore essential to take the time to ensure that the research question addresses what you actually want to study. Doing so will increase the likelihood of obtaining meaningful results.

     

    In this first component of the course project, you formulate questions to address a particular nursing issue or problem. You use the PICOT model—patient/population, intervention/issue, comparison, and outcome—outlined in the weekly Learning Resources to design your questions.

     

    To prepare:

     

    Review the article, “Formulating the Evidence Based Practice Question: A Review of the Frameworks,” found in the Learning Resources for Week 2. Focus on the PICOT model for guiding the development of research questions.

     

    Review the section beginning on page of the course text, 75 titled, “Developing and Refining Research Problems” in the course text, which focuses on analyzing the feasibility of a research problem.

    Reflect on an issue or problem that you have noticed in your nursing practice. Consider the significance of this issue or problem.

    Generate at least 5 questions that relate to the issue that you have identified. Use the criteria in your course text to select one question that would be most appropriate in terms of significance, feasibility, and interest. Be prepared to explain your rationale.

    Formulate a preliminary PICOT question—one that is answerable—based on your analysis. What are the PICOT variables (patient/population, intervention/issue, comparison, and outcome) for this question?
    Note:
    Not all of these variables may be appropriate to every question. Be sure to analyze which are and are not relevant to your specific question. NURS 5052/NURS 6052: Essentials of Evidence-Based Practice.

    Using the PICOT variables that you determined for your question, develop a list of at least 10 keywords that could be used when conducting a literature search to investigate current research pertaining to the question.

    To complete:

    Write a 3- to 4-page paper that includes the following:

    A summary of your area of interest, an identification of the problem that you have selected, and an explanation of the significance of this problem for nursing practice

    The 5 questions that you have generated, and a description of how you analyzed them for feasibility

    Your preliminary PICOT question and a description of each PICOT variable relevant to your question

    At least 10 possible keywords that could be used when conducting a literature search for your PICOT question and a rationale for your selections NURS 5052/NURS 6052: Essentials of Evidence-Based Practice

    Part 1 of the Course Project is due by
    Day 7
    of
    Week 2
    . It will also be a component of your
    Portfolio Assignment
    for this course, which is due by
    Day 7
    of
    Week 10
    .

    Reference:

    Davies, K. S. (2011). Formulating the evidence based practice question: A review of the frameworks.
    Evidence Based Library and Information Practice, 6
    (2), 75–80. Retrieved from
    https://ejournals.library.ualberta.ca/index.php/EBLIP/article/viewFile/9741/8144

    Course Project: Part 2—Literature Review

     

    The literature review is a critical piece in the research process because it helps a researcher determine what is currently known about a topic and identify gaps or further questions. Conducting a thorough literature review can be a time-consuming process, but the effort helps establish the foundation for everything that will follow. For this part of your Course Project, you will conduct a brief literature review to find information on the question that you developed in Week 2. This will provide you with experience in searching databases and identifying applicable resources. NURS 5052/NURS 6052: Essentials of Evidence-Based Practice.

    To prepare:

    Review the information in Chapter 5 of the course text
    ,
    focusing on the steps for conducting a literature review and for compiling your findings.

    Using the question that you selected in your Week 2 Project (Part 1 of the Course Project), locate 5 or more full-text research articles that are relevant to your PICOT question. Include at least 1 systematic review and 1 integrative review if possible. Use the search tools and techniques mentioned in your readings this week to enhance the comprehensiveness and objectivity of your review. You may gather these articles from any appropriate source, but make sure at least 3 of these articles are available as full-text versions through Walden Library’s databases. NURS 5052/NURS 6052: Essentials of Evidence-Based Practice.

    Read through the articles carefully. Eliminate studies that are not appropriate and add others to your list as needed. Although you may include more, you are expected to include a minimum of five articles. Complete a literature review summary table using the
    Literature Review Summary Table Template
    located in this week’s Learning Resources.

    Prepare to summarize and synthesize the literature using the information on writing a literature review found in Chapter 5 of the course text.

    To complete:

    Develop a 2- to 3-page literature review that includes the following:

    A synthesis of what the studies reveal about the current state of knowledge on the question that you developed

    Point out inconsistencies and contradictions in the literature and offer possible explanations for inconsistencies.

    Preliminary conclusions on whether the evidence provides strong support for a change in practice or whether further research is needed to adequately address your inquiry

    Your literature review summary table with all references formatted in correct APA style

    Note:
    Certain aspects of conducting a standard review of literature have not yet been covered in this course. Therefore, while you are invited to critically examine any aspect of the studies (e.g., a study’s design, appropriateness of the theoretic framework, data sampling methods), your conclusion should be considered preliminary. Bear in mind that five studies are typically not enough to reflect the full range of knowledge on a particular question and you are not expected to be familiar enough with research methodology to conduct a comprehensive evaluation of all aspects of the studies. NURS 5052/NURS 6052: Essentials of Evidence-Based Practice.

    Part 2 of the Course Project is due by
    Day 7
    of
    Week

    5.
    It will also be a component in your portfolio assignment in this course, which is due by
    Day 7
    of Week 10.

    Course Project Part 3 – Translating Evidence Into Practice

    Now that you have located available research on your PICOT question, you will examine what the research indicates about nursing practices. Connecting research evidence and findings to actual decisions and tasks that nurses complete in their daily practice is essentially what evidence-based practice is all about. This final component of the Course Project asks you to translate the evidence and data from your literature review into authentic practices that can be adopted to improve health care outcomes. In addition, you will also consider possible methods and strategies for disseminating evidence-based practices to your colleagues and to the broader health care field.

    To prepare:

    Consider Parts 1 and 2 of your Course Project. How does the research address your PICOT question?

    With your PICOT question in mind, identify at least one nursing practice that is supported by the evidence in two or more of the articles from your literature review. Consider what the evidence indicates about how this practice contributes to better outcomes. NURS 5052/NURS 6052: Essentials of Evidence-Based Practice.

    Explore possible consequences of failing to adopt the evidence-based practice that you identified.

    Consider how you would disseminate information about this evidence-based practice throughout your organization or practice setting. How would you communicate the importance of the practice?

    To complete:

    In a 3- to 4-page paper:

    Restate your PICOT question and its significance to nursing practice.

    Summarize the findings from the articles that you selected for your literature review. Describe at least one nursing practice that is supported by the evidence in the articles. Justify your response with specific references to at least 2 of the articles.

    Explain how the evidence-based practice that you identified contributes to better outcomes. In addition, identify potential negative outcomes that could result from failing to use the evidence-based practice.

    Outline the strategy for disseminating the evidence-based practice that you identified throughout your practice setting. Explain how you would communicate the importance of the practice to your colleagues. Describe how you would move from disseminating the information to implementing the evidence-based practice within your organization. How would you address concerns and opposition to the change in practice?

    Part 3 of the Course Project is due by
    Day 7
    of
    Week

    10
    . It should be combined with the other two components of the Course Project and turned in as your
    Portfolio Assignment
    for this course.
    Note:
     In addition, include a 1-page summary of your project. NURS 5052/NURS 6052: Essentials of Evidence-Based Practice.

    For this final iteration you will need to:

     

    Submit your paper to Grammarly and Turnitin through the Walden Writing Center. Based on the Grammarly and Turnitin reports, revise your paper as necessary.

    Reminder:
    The School of Nursing requires that all papers submitted include a title page, introduction, summary, and references. The
    School of Nursing Sample Paper
    provided at the Walden Writing Center provides an example of those required elements (available from the Walden University website found in this week’s Learning Resources). All papers submitted must use this formatting.

    Note:
    The Course Project will be your
    Portfolio Assignment
    for this course. NURS 5052/NURS 6052: Essentials of Evidence-Based Practice.