A pharmaceutical company is developing a gene therapy
protocol for male pattern baldness. The product is a cream that contains a
retrovirus similar to the viruses that cause the common cold. The virus
contains a gene that promotes hair growth. To be effective, the cream needs to
be rubbed on the bald skin and not removed (by washing) for at least three
hours. In animal studies, the cream has successfully grown hair on bald rodents
with few side effects, other than some respiratory symptoms similar to the common
cold. The company would like to begin phase I trials on healthy, adult men with
male pattern baldness.
• Do you see any potential ethical and social problems with
this gene therapy study?
• If you were an IRB member, would you approve it?
• What else would you like to know about this research
before you make a decision?
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