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**files (3)** – ## MilestoneOne.docx – ## Milestone21.docx – FinalProjectGuidelinesandRubric.docx **## MilestoneOne.docx** 2 **Milestone One: Organ System Assessment** Danitza Fernandez-Andes SNHU Intro to Anatomy & Physiology Professor: Tina Lane January 15, 2026 **Milestone One: Organ System Asses…

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Assignment Prompt & Instructions

**files (3)**

– ## MilestoneOne.docx

– ## Milestone21.docx

– FinalProjectGuidelinesandRubric.docx

**## MilestoneOne.docx**

2

**Milestone One: Organ System Assessment**

Danitza Fernandez-Andes

SNHU

Intro to Anatomy & Physiology

Professor: Tina Lane

January 15, 2026

**Milestone One: Organ System Assessment**

**Chosen Organ System:** _Respiratory System_

**Anatomy (Location, Organs, Structures, Cells/Tissues)**

·
**Anatomical location:** The respiratory system is located primarily in the
**thoracic cavity**, with the upper airway beginning in the
**nasal cavity** of the head and extending down into the chest.

·
**Upper respiratory tract structures:** Includes the nose/nasal cavity, paranasal sinuses, pharynx, and larynx, which filter, warm, and humidify inhaled air.

·
**Lower respiratory tract structures:** Includes the trachea, bronchi, bronchioles, and lungs, which conduct air to gas-exchange surfaces .

·
**Primary organs:** The lungs are the main organs of respiration and contain the alveoli where gas exchange occurs.

·
**Alveoli structure:** **Alveoli** are microscopic air sacs surrounded by capillaries, forming the respiratory membrane for oxygen and carbon dioxide diffusion.

·
**Key tissue type (epithelial tissue):** The trachea and bronchi are lined with pseudostratified ciliated columnar epithelium, which helps trap and move mucus upward.

·
**Key cell type (Type I pneumocytes):** Type I alveolar cells form thin walls that allow rapid diffusion of gases.

·
**Key cell type (Type II pneumocytes):** Type II alveolar cells secrete surfactant, reducing surface tension and preventing alveolar collapse.

·
**Key defense cells:** **Alveolar macrophages** remove debris and pathogens to support immune defense in the lungs .

·
**Supporting structures:** The diaphragm and intercostal muscles assist ventilation by changing thoracic volume and pressure.

![Human Respiratory System – GeeksforGeeks](https://www.sweetstudy.com/questions/assigment-apa-seven-all-instructions-attached-20962391)**“Labeled respiratory system location relative to other organ systems”**

**Physiology (Major Functions + One Visual Function)**

·
**Primary function 1 (gas exchange):** The respiratory system performs oxygen uptake and carbon dioxide removal through diffusion across the alveolar-capillary membrane.

·
**Primary function 2 (ventilation mechanics):** Breathing occurs through inhalation and exhalation, driven by pressure changes created by the diaphragm and chest wall expansion .

·
**Primary function 3 (pH regulation):** By controlling CO₂ levels, the respiratory system helps regulate acid–base balance in the blood .

·
**Primary function 4 (air conditioning and protection):** The airway filters particles and pathogens using mucus and cilia, reducing respiratory infection risk .

![Oxygen Gas Exchange Stock Illustrations – 785 Oxygen Gas Exchange Stock Illustrations, Vectors & Clipart – Dreamstime](https://www.sweetstudy.com/questions/assigment-apa-seven-all-instructions-attached-20962391)**“Labeled diagram illustrating one function (alveolar gas exchange)”**

Reference

Moussavi, Z. (2022). Anatomy and Physiology of Respiratory System. In
_Fundamentals of Respiratory System and Sounds Analysis_ (pp. 1-8). Cham: Springer International Publishing.

## image1.png

## image2.jpeg

**## Milestone21.docx**

2

**Secondary Organ System: Cardiovascular System**

Danitza Fernandez-Andes

SNHU

Intro to Anatomy & Physiology

Professor: Tina Lane

January 25, 2026

## **Organ System Interrelationship and Disease Assessment**

**Primary Organ System: Respiratory System**

**Secondary Organ System: Cardiovascular System**

**Homeostatic Interrelationship and Physiological Interactions**

· The pulmonary and circulatory systems function as integrated, bringing oxygen into the tissues and transporting carbon dioxide out of the body.

· Additional blood is oxygenated at the lungs by gas exchange in the alveoli and then pumped through the heart for systemic circulation.

· The CO2 generated from the metabolism in cells is carried by the cardiovascular system back to the lung for expiration.

· It is the hemoglobin in red blood cells that carries oxygen from the lungs and delivers it to peripheral tissues.

· The pulmonary circulation between the heart and lungs provides a route for gaseous exchange to occur.

· Both mechanisms are for the purpose of maintaining blood pH with respect to equilibrium with carbon dioxide.

· More physical activity causes the body to breathe harder and faster in order to keep up with its heart rate.

· Good lung ventilation is important for optimal CO and tissue perfusion.

· The respiratory system impacts blood pressure via oxygen delivery and vasomotor tone.

· Impairment of the latter by dysfunction in either system leads to disturbances in oxygen supply and cellular metabolism.

**Significance of Human Health**

· This relationship maintains cellular respiration, energy production, and organ function.

· Proper interaction prevents hypoxia, acidosis, and organ failure.

· Long-term survival depends on efficient coordination between breathing and circulation.

**Disease Affecting the Primary System: Chronic Obstructive Pulmonary Disease (COPD)**

**Description of the Condition**

· Chronic obstructive pulmonary disease (COPD) is a progressive lung condition with airways limitation persistency.

· It comprises chronic bronchitis and emphysema.

· COPD, characterized by persistent lungs airflow limitation, usually affects adults aged 40 and over who have been exposed to smoking or long-term pollutants.

· Presenting symptoms are persistent cough, shortness of breath, wheezing and fatigue.

**Causes**

· The leading cause of COPD is long-term cigarette smoking.

· Environmental pollutants, occupational dust, and chemical exposure contribute to disease development (GOLD, 2024).

· Genetic factors, such as alpha-1 antitrypsin deficiency, also increase risk.

· Recurrent respiratory infections may worsen disease progression.

**Implications and Consequences**

· COPD reduces lung elasticity and airway patency, impairing oxygen exchange.

· Chronic hypoxia increases cardiac workload, leading to pulmonary hypertension and right-sided heart failure.

· Patients’ experience decreased exercise tolerance and quality of life.

· Frequent hospitalizations and long-term oxygen therapy increase healthcare costs.

· COPD contributes significantly to disability and premature mortality in the United States.

**Prevalence in the United States**

· About 14.2 million U.S. adults have been diagnosed with COPD.

· Another 7–8 million people are believed to be undiagnosed (CDC, 2023).

· Among older, smoking and low socioeconomic population are those with high prevalence levels.

**References**

Centers for Disease Control and Prevention. (2023).
_Chronic obstructive pulmonary disease (COPD) data and statistics_. https://www.cdc.gov/copd/data.html

Global Initiative for Chronic Obstructive Lung Disease. (2024).
_Global strategy for the diagnosis, management, and prevention of COPD (2024 report)_.
[https://goldcopd.org/2024-gold-report/](https://goldcopd.org/2024-gold-report/)

**FinalProjectGuidelinesandRubric.docx**

This file is too large to display. [View in new window](https://www.sweetstudy.com/files/finalprojectguidelinesandrubric-docx-10503681)

**FinalProjectGuidelinesandRubric.docx**

This file is too large to display. [View in new window](https://www.sweetstudy.com/files/finalprojectguidelinesandrubric-docx-10503681)

**## MilestoneOne.docx**

2

**Milestone One: Organ System Assessment**

Danitza Fernandez-Andes

SNHU

Intro to Anatomy & Physiology

Professor: Tina Lane

January 15, 2026

**Milestone One: Organ System Assessment**

**Chosen Organ System:** _Respiratory System_

**Anatomy (Location, Organs, Structures, Cells/Tissues)**

·
**Anatomical location:** The respiratory system is located primarily in the
**thoracic cavity**, with the upper airway beginning in the
**nasal cavity** of the head and extending down into the chest.

·
**Upper respiratory tract structures:** Includes the nose/nasal cavity, paranasal sinuses, pharynx, and larynx, which filter, warm, and humidify inhaled air.

·
**Lower respiratory tract structures:** Includes the trachea, bronchi, bronchioles, and lungs, which conduct air to gas-exchange surfaces .

·
**Primary organs:** The lungs are the main organs of respiration and contain the alveoli where gas exchange occurs.

·
**Alveoli structure:** **Alveoli** are microscopic air sacs surrounded by capillaries, forming the respiratory membrane for oxygen and carbon dioxide diffusion.

·
**Key tissue type (epithelial tissue):** The trachea and bronchi are lined with pseudostratified ciliated columnar epithelium, which helps trap and move mucus upward.

·
**Key cell type (Type I pneumocytes):** Type I alveolar cells form thin walls that allow rapid diffusion of gases.

·
**Key cell type (Type II pneumocytes):** Type II alveolar cells secrete surfactant, reducing surface tension and preventing alveolar collapse.

·
**Key defense cells:** **Alveolar macrophages** remove debris and pathogens to support immune defense in the lungs .

·
**Supporting structures:** The diaphragm and intercostal muscles assist ventilation by changing thoracic volume and pressure.

![Human Respiratory System – GeeksforGeeks](https://www.sweetstudy.com/questions/assigment-apa-seven-all-instructions-attached-20962391)**“Labeled respiratory system location relative to other organ systems”**

**Physiology (Major Functions + One Visual Function)**

·
**Primary function 1 (gas exchange):** The respiratory system performs oxygen uptake and carbon dioxide removal through diffusion across the alveolar-capillary membrane.

·
**Primary function 2 (ventilation mechanics):** Breathing occurs through inhalation and exhalation, driven by pressure changes created by the diaphragm and chest wall expansion .

·
**Primary function 3 (pH regulation):** By controlling CO₂ levels, the respiratory system helps regulate acid–base balance in the blood .

·
**Primary function 4 (air conditioning and protection):** The airway filters particles and pathogens using mucus and cilia, reducing respiratory infection risk .

![Oxygen Gas Exchange Stock Illustrations – 785 Oxygen Gas Exchange Stock Illustrations, Vectors & Clipart – Dreamstime](https://www.sweetstudy.com/questions/assigment-apa-seven-all-instructions-attached-20962391)**“Labeled diagram illustrating one function (alveolar gas exchange)”**

Reference

Moussavi, Z. (2022). Anatomy and Physiology of Respiratory System. In
_Fundamentals of Respiratory System and Sounds Analysis_ (pp. 1-8). Cham: Springer International Publishing.

## image1.png

## image2.jpeg

**## Milestone21.docx**

2

**Secondary Organ System: Cardiovascular System**

Danitza Fernandez-Andes

SNHU

Intro to Anatomy & Physiology

Professor: Tina Lane

January 25, 2026

## **Organ System Interrelationship and Disease Assessment**

**Primary Organ System: Respiratory System**

**Secondary Organ System: Cardiovascular System**

**Homeostatic Interrelationship and Physiological Interactions**

· The pulmonary and circulatory systems function as integrated, bringing oxygen into the tissues and transporting carbon dioxide out of the body.

· Additional blood is oxygenated at the lungs by gas exchange in the alveoli and then pumped through the heart for systemic circulation.

· The CO2 generated from the metabolism in cells is carried by the cardiovascular system back to the lung for expiration.

· It is the hemoglobin in red blood cells that carries oxygen from the lungs and delivers it to peripheral tissues.

· The pulmonary circulation between the heart and lungs provides a route for gaseous exchange to occur.

· Both mechanisms are for the purpose of maintaining blood pH with respect to equilibrium with carbon dioxide.

· More physical activity causes the body to breathe harder and faster in order to keep up with its heart rate.

· Good lung ventilation is important for optimal CO and tissue perfusion.

· The respiratory system impacts blood pressure via oxygen delivery and vasomotor tone.

· Impairment of the latter by dysfunction in either system leads to disturbances in oxygen supply and cellular metabolism.

**Significance of Human Health**

· This relationship maintains cellular respiration, energy production, and organ function.

· Proper interaction prevents hypoxia, acidosis, and organ failure.

· Long-term survival depends on efficient coordination between breathing and circulation.

**Disease Affecting the Primary System: Chronic Obstructive Pulmonary Disease (COPD)**

**Description of the Condition**

· Chronic obstructive pulmonary disease (COPD) is a progressive lung condition with airways limitation persistency.

· It comprises chronic bronchitis and emphysema.

· COPD, characterized by persistent lungs airflow limitation, usually affects adults aged 40 and over who have been exposed to smoking or long-term pollutants.

· Presenting symptoms are persistent cough, shortness of breath, wheezing and fatigue.

**Causes**

· The leading cause of COPD is long-term cigarette smoking.

· Environmental pollutants, occupational dust, and chemical exposure contribute to disease development (GOLD, 2024).

· Genetic factors, such as alpha-1 antitrypsin deficiency, also increase risk.

· Recurrent respiratory infections may worsen disease progression.

**Implications and Consequences**

· COPD reduces lung elasticity and airway patency, impairing oxygen exchange.

· Chronic hypoxia increases cardiac workload, leading to pulmonary hypertension and right-sided heart failure.

· Patients’ experience decreased exercise tolerance and quality of life.

· Frequent hospitalizations and long-term oxygen therapy increase healthcare costs.

· COPD contributes significantly to disability and premature mortality in the United States.

**Prevalence in the United States**

· About 14.2 million U.S. adults have been diagnosed with COPD.

· Another 7–8 million people are believed to be undiagnosed (CDC, 2023).

· Among older, smoking and low socioeconomic population are those with high prevalence levels.

**References**

Centers for Disease Control and Prevention. (2023).
_Chronic obstructive pulmonary disease (COPD) data and statistics_. https://www.cdc.gov/copd/data.html

Global Initiative for Chronic Obstructive Lung Disease. (2024).
_Global strategy for the diagnosis, management, and prevention of COPD (2024 report)_.
[https://goldcopd.org/2024-gold-report/](https://goldcopd.org/2024-gold-report/)

**FinalProjectGuidelinesandRubric.docx**

This file is too large to display. [View in new window](https://www.sweetstudy.com/files/finalprojectguidelinesandrubric-docx-10503681)

**## MilestoneOne.docx**

2

**Milestone One: Organ System Assessment**

Danitza Fernandez-Andes

SNHU

Intro to Anatomy & Physiology

Professor: Tina Lane

January 15, 2026

**Milestone One: Organ System Assessment**

**Chosen Organ System:** _Respiratory System_

**Anatomy (Location, Organs, Structures, Cells/Tissues)**

·
**Anatomical location:** The respiratory system is located primarily in the
**thoracic cavity**, with the upper airway beginning in the
**nasal cavity** of the head and extending down into the chest.

·
**Upper respiratory tract structures:** Includes the nose/nasal cavity, paranasal sinuses, pharynx, and larynx, which filter, warm, and humidify inhaled air.

·
**Lower respiratory tract structures:** Includes the trachea, bronchi, bronchioles, and lungs, which conduct air to gas-exchange surfaces .

·
**Primary organs:** The lungs are the main organs of respiration and contain the alveoli where gas exchange occurs.

·
**Alveoli structure:** **Alveoli** are microscopic air sacs surrounded by capillaries, forming the respiratory membrane for oxygen and carbon dioxide diffusion.

·
**Key tissue type (epithelial tissue):** The trachea and bronchi are lined with pseudostratified ciliated columnar epithelium, which helps trap and move mucus upward.

·
**Key cell type (Type I pneumocytes):** Type I alveolar cells form thin walls that allow rapid diffusion of gases.

·
**Key cell type (Type II pneumocytes):** Type II alveolar cells secrete surfactant, reducing surface tension and preventing alveolar collapse.

·
**Key defense cells:** **Alveolar macrophages** remove debris and pathogens to support immune defense in the lungs .

·
**Supporting structures:** The diaphragm and intercostal muscles assist ventilation by changing thoracic volume and pressure.

![Human Respiratory System – GeeksforGeeks](https://www.sweetstudy.com/questions/assigment-apa-seven-all-instructions-attached-20962391)**“Labeled respiratory system location relative to other organ systems”**

**Physiology (Major Functions + One Visual Function)**

·
**Primary function 1 (gas exchange):** The respiratory system performs oxygen uptake and carbon dioxide removal through diffusion across the alveolar-capillary membrane.

·
**Primary function 2 (ventilation mechanics):** Breathing occurs through inhalation and exhalation, driven by pressure changes created by the diaphragm and chest wall expansion .

·
**Primary function 3 (pH regulation):** By controlling CO₂ levels, the respiratory system helps regulate acid–base balance in the blood .

·
**Primary function 4 (air conditioning and protection):** The airway filters particles and pathogens using mucus and cilia, reducing respiratory infection risk .

![Oxygen Gas Exchange Stock Illustrations – 785 Oxygen Gas Exchange Stock Illustrations, Vectors & Clipart – Dreamstime](https://www.sweetstudy.com/questions/assigment-apa-seven-all-instructions-attached-20962391)**“Labeled diagram illustrating one function (alveolar gas exchange)”**

Reference

Moussavi, Z. (2022). Anatomy and Physiology of Respiratory System. In
_Fundamentals of Respiratory System and Sounds Analysis_ (pp. 1-8). Cham: Springer International Publishing.

## image1.png

## image2.jpeg

**## Milestone21.docx**

2

**Secondary Organ System: Cardiovascular System**

Danitza Fernandez-Andes

SNHU

Intro to Anatomy & Physiology

Professor: Tina Lane

January 25, 2026

## **Organ System Interrelationship and Disease Assessment**

**Primary Organ System: Respiratory System**

**Secondary Organ System: Cardiovascular System**

**Homeostatic Interrelationship and Physiological Interactions**

· The pulmonary and circulatory systems function as integrated, bringing oxygen into the tissues and transporting carbon dioxide out of the body.

· Additional blood is oxygenated at the lungs by gas exchange in the alveoli and then pumped through the heart for systemic circulation.

· The CO2 generated from the metabolism in cells is carried by the cardiovascular system back to the lung for expiration.

· It is the hemoglobin in red blood cells that carries oxygen from the lungs and delivers it to peripheral tissues.

· The pulmonary circulation between the heart and lungs provides a route for gaseous exchange to occur.

· Both mechanisms are for the purpose of maintaining blood pH with respect to equilibrium with carbon dioxide.

· More physical activity causes the body to breathe harder and faster in order to keep up with its heart rate.

· Good lung ventilation is important for optimal CO and tissue perfusion.

· The respiratory system impacts blood pressure via oxygen delivery and vasomotor tone.

· Impairment of the latter by dysfunction in either system leads to disturbances in oxygen supply and cellular metabolism.

**Significance of Human Health**

· This relationship maintains cellular respiration, energy production, and organ function.

· Proper interaction prevents hypoxia, acidosis, and organ failure.

· Long-term survival depends on efficient coordination between breathing and circulation.

**Disease Affecting the Primary System: Chronic Obstructive Pulmonary Disease (COPD)**

**Description of the Condition**

· Chronic obstructive pulmonary disease (COPD) is a progressive lung condition with airways limitation persistency.

· It comprises chronic bronchitis and emphysema.

· COPD, characterized by persistent lungs airflow limitation, usually affects adults aged 40 and over who have been exposed to smoking or long-term pollutants.

· Presenting symptoms are persistent cough, shortness of breath, wheezing and fatigue.

**Causes**

· The leading cause of COPD is long-term cigarette smoking.

· Environmental pollutants, occupational dust, and chemical exposure contribute to disease development (GOLD, 2024).

· Genetic factors, such as alpha-1 antitrypsin deficiency, also increase risk.

· Recurrent respiratory infections may worsen disease progression.

**Implications and Consequences**

· COPD reduces lung elasticity and airway patency, impairing oxygen exchange.

· Chronic hypoxia increases cardiac workload, leading to pulmonary hypertension and right-sided heart failure.

· Patients’ experience decreased exercise tolerance and quality of life.

· Frequent hospitalizations and long-term oxygen therapy increase healthcare costs.

· COPD contributes significantly to disability and premature mortality in the United States.

**Prevalence in the United States**

· About 14.2 million U.S. adults have been diagnosed with COPD.

· Another 7–8 million people are believed to be undiagnosed (CDC, 2023).

· Among older, smoking and low socioeconomic population are those with high prevalence levels.

**References**

Centers for Disease Control and Prevention. (2023).
_Chronic obstructive pulmonary disease (COPD) data and statistics_. https://www.cdc.gov/copd/data.html

Global Initiative for Chronic Obstructive Lung Disease. (2024).
_Global strategy for the diagnosis, management, and prevention of COPD (2024 report)_.
[https://goldcopd.org/2024-gold-report/](https://goldcopd.org/2024-gold-report/)

**FinalProjectGuidelinesandRubric.docx**

This file is too large to display. [View in new window](https://www.sweetstudy.com/files/finalprojectguidelinesandrubric-docx-10503681)

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